Evidence map›Paper›PMID 34829259›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Novel Nile Blue Analogue Stains Yeast Vacuolar Membrane, Endoplasmic Reticulum, and Lipid Droplets, Inducing Cell Death through Vacuole Membrane Permeabilization.

João Carlos Canossa Ferreira, Carla Lopes, Ana Preto, Maria Sameiro Torres Gonçalves, Maria João Sousa

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Combining Fluconazole with Benzo[Molecules (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Novel Benzo[International journal of molecular sciences · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

João Carlos Canossa FerreiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.
Carla LopesCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.
Ana PretoCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-7302-0630
Maria Sameiro Torres GonçalvesCentre of Chemistry, Department of Chemistry, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0003-2048-1190
Maria João SousaCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-9424-4150
University of Minho · PT

Funding

Fundação para a Ciência e Tecnologia PTDC/QUIQIN/28662/2017Fundação para a Ciência e Tecnologia SFRH/BD/133207/2017Fundação para a Ciência e Tecnologia UIDB/04050/2020Fundação para a Ciência e Tecnologia UID/BIA/04050/2019Fundação para a Ciência e Tecnologia UID/QUI/00686/2016Fundação para a Ciência e Tecnologia UID/ QUI/0686/2019
6 · The paper itself

Abstract

Phenoxazine derivatives such as Nile Blue analogues are assumed to be increasingly relevant in cell biology due to their fluorescence staining capabilities and antifungal and anticancer activities. However, the mechanisms underlying their effects remain poorly elucidated. Using

Indexed as

benzo[a]phenoxazine derivativecell death mechanismNile Blue analoguevacuole/lysosome membrane permeabilizationyeast as a eukaryotic cell model

Identifiers

PMID34829259
PMCPMC8623074
OpenAlexW3213737779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.