Evidence map›Paper›PMID 34829085›Full record

ArticleFoods (Basel, Switzerland)2021

Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies.

Ana C Gonçalves, Radhia Aitfella Lahlou, Gilberto Alves, Cristina Garcia-Viguera, Diego A Moreno, Luís R Silva

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  9. Zimbro (International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Ana C GonçalvesCICS-UBI-Health Sciences Research Centre, Department of Medical Science, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0001-7795-795X
Radhia Aitfella LahlouChemistry Department, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0002-6911-6947
Gilberto AlvesCICS-UBI-Health Sciences Research Centre, Department of Medical Science, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0002-4213-0714
Cristina Garcia-VigueraPhytochemistry and Healthy Foods Laboratory, Food Science and Technology Department, CEBAS-CSIC, Campus Universitario de Espinardo, 30100 Espinardo, Murcia, Spain.ORCID 0000-0002-4751-3917
Diego A MorenoPhytochemistry and Healthy Foods Laboratory, Food Science and Technology Department, CEBAS-CSIC, Campus Universitario de Espinardo, 30100 Espinardo, Murcia, Spain.ORCID 0000-0002-6547-8764
Luís R SilvaCICS-UBI-Health Sciences Research Centre, Department of Medical Science, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0001-5264-3516
University of Beira Interior · PTCentro de Edafología y Biología Aplicada del Segura · ES

Funding

Fundação para a Ciência e Tecnologia 2020.04947.BD
6 · The paper itself

Abstract

The aim of this study was to determine the grain composition and (poly)phenolic profile of pollen from Abrantes (Portugal), as well as its antioxidative and antidiabetic properties, and abilities to protect human erythrocytes against induced hemoglobin oxidation, lipid peroxidation, and hemolysis. The phytochemical profile of the Abrantes' bee pollen revealed twenty phenolic compounds, identified by high-performance liquid chromatography with electrospray ionization mass spectrometry coupled with photodiode array detection. Among them, quercetin derivatives were the most abundant. Concerning the biological potential, the pollen extract showed notable capacity for 2,2-diphenyl-1-picrylhydrazyl, nitric oxide, and superoxide radicals, as well as for inhibition of α-glucosidase action, and protection of human erythrocytes against oxidative damage. Non-cytotoxic effects regarding the NHDF normal cell line, human adenocarcinoma Caco-2, and human liver HepG2 cells were observed. The results obtained contributed to further research on modes of action related to oxidative damage and metabolic health problems, to generate deeper knowledge of potential health-promoting effects to develop novel pharmaceutical drugs, nutraceuticals, and dietary supplements.

Indexed as

antioxidant effectsbee pollenbiological potentialfunctional foodphenolic characterization

Identifiers

PMID34829085
PMCPMC8624898
OpenAlexW3213040372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.