ArticleFoods (Basel, Switzerland)2021
Lectin Activity in Commonly Consumed Plant-Based Foods: Calling for Method Harmonization and Risk Assessment.
Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 42 citations in OpenAlex.
- Mitogenic potential of endogenous GlcNAc-specific lectins from rat brain cell nuclear membranes.Molecular biology reports · 2026Article
- Comprehensive Insights into Plant-Derived Bioactive Peptides: Sources, Technological Strategies, and Health Implications.Molecules (Basel, Switzerland) · 2026Review
- Gap Analysis of Metabolic Conversions of Off-Flavors and Antinutrients in Plant-Based Substrates.Comprehensive reviews in food science and food safety · 2026Review
- Severe red kidney beans toxicity in an 8-year-old girl: a rare case of hypovolemic shock and prerenal acute kidney injury.International journal of emergency medicine · 2026Article
- Toward Standardized Measurement of Active Phytohemagglutinin in Common Bean,Foods (Basel, Switzerland) · 2025Article
- Adhering to recommended dietary protein intake for optimizing human health benefitsRSC advances · 2025Review
- Safety evaluation of pea fibre concentrate (FIPEA) as food additive.EFSA journal. European Food Safety Authority · 2025Article
- Article
- Legume lectin phytohemagglutinin reduces transepithelial electrical resistance by counteracting the chaperone function of heat shock protein-70.Journal of nutritional science · 2025Article
- CRISPR/Cas9-mediated inactivation of the soybean agglutininFrontiers in plant science · 2025Article
- Unveiling the nutritional spectrum: A comprehensive analysis of protein quality and antinutritional factors in three varieties of quinoa (Food chemistry: X · 2024Article
- Wheat Germ Agglutinin (WGA): Its Nature, Biological Role, Significance in Human Nutrition, and Possibility to Be Used as Marker of Whole-Grain Status in Wheat-Based Foods.Foods (Basel, Switzerland) · 2024Review
- Local Sources of Protein in Low- and Middle-Income Countries: How to Improve the Protein Quality?Current developments in nutrition · 2024Article
- From Foodborne Disease Outbreak (FBDO) to Investigation: The Plant Toxin Trap, Brittany, France, 2018.Toxins · 2023Article
- Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis.Chemical research in toxicology · 2023Article
- Nutrient synergy: definition, evidence, and future directions.Frontiers in nutrition · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lectins are ubiquitous proteins characterized through their ability to bind different types of carbohydrates. It is well known that active lectins from insufficiently prepared legumes can cause adverse human health effects. The objective of this study was to determine the activity of lectins in samples across plant families representing commercially available edible plants, and the feasibility of inactivating lectins through soaking and boiling. Lectins were extracted from the plant families Adoxaceae, Amaranthaceae, Cannabaceae, Fabaceae, Gramineae, Lamiaceae, Linaceae, Pedaliaceae, and Solanaceae. A hemagglutination assay based on non-treated or trypsin treated rabbit erythrocytes was used to measure the lectin activity. The results showed the highest lectin activity in species from the Fabaceae family and demonstrated that soaking and boiling have an effect on the levels of active lectins. This is the first large study that combines lectin activity obtained from two different assays with raw and processed edible plants. In addition, we examined the current risk assessment, and regulations necessary for an adequate official reporting of results. We encourage the scientific community to further explore this field and agree on harmonized methods for analysis and interpretation, and hope that our methodology can initiate this development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.