ReviewFoods (Basel, Switzerland)2021
Non-IgE-Mediated Gastrointestinal Food Protein-Induced Allergic Disorders. Clinical Perspectives and Analytical Approaches.
Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- EGR1 regulates degranulation and mediator release in C48/80-induced pseudo-allergic reactions.Immunologic research · 2026Article
- Micronutrient status and growth outcomes in children with cow's milk allergy: beyond elimination diets.Frontiers in nutrition · 2026Review
- Prevalence Clinical Syndromes and Outcomes of Cow's Milk Allergy in Children: A Four-Year Follow-Up.Nutrients · 2025Article
- Sensitization to common food allergens in infants with food protein-induced allergic proctocolitis: A prospective study.Asia Pacific allergy · 2025Article
- Food Hypersensitivity: Distinguishing Allergy from Intolerance, Main Characteristics, and Symptoms-A Narrative Review.Nutrients · 2025Review
- Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study.BMJ paediatrics open · 2025Article
- Food Protein-Induced Allergic Proctocolitis: Real-World Experience from an Italian Cohort.Nutrients · 2024Observational
- Non-immunoglobulin E-mediated food allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024Review
- Cord blood methylation at TNFRSF17 is associated with early allergic phenotypes.Immunologic research · 2024Article
- The impact of high-IgE levels on metabolome and microbiome in experimental allergic enteritis.Allergy · 2024Article
- Dietary Intervention during Weaning and Development of Food Allergy: What Is the State of the Art?International journal of molecular sciences · 2024Review
- Analysis of the characteristics of intestinal microbiota after oral tolerance in infants with food protein-induced proctocolitis.Frontiers in pediatrics · 2024Article
- Allergic Proctocolitis: Literature Review and Proposal of a Diagnostic-Therapeutic Algorithm.Life (Basel, Switzerland) · 2023Review
- Further Insights into the Gut Microbiota of Cow's Milk Allergic Infants: Analysis of Microbial Functionality and Its Correlation with Three Fecal Biomarkers.International journal of molecular sciences · 2023Article
- Molecular Approaches for Food Protein Allergenicity Assessment and the Diagnosis and Treatment of Food Allergies.Foods (Basel, Switzerland) · 2023Article
- Perspectives on Non-IgE-Mediated Gastrointestinal Food Allergy in Pediatrics: A Review of Current Evidence and Guidelines.Journal of asthma and allergy · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Non-IgE-mediated gastrointestinal food allergy (non-IgE-GI-FA) is the name given to a series of pathologies whose main entities are food protein-induced allergic proctocolitis (FPIAP), food protein-induced enteropathy (FPE), and food protein-induced enterocolitis syndrome (FPIES). These are more uncommon than IgE-mediated food allergies, their mechanisms remain largely unknown, and their diagnosis is mainly done by clinical history, due to the lack of specific biomarkers. In this review, we present the latest advances found in the literature about clinical aspects, the current diagnosis, and treatment options of non-IgE-GI-FAs. We discuss the use of animal models, the analysis of gut microbiota, omics techniques, and fecal proteins with a focus on understanding the pathophysiological mechanisms of these pathologies and obtaining possible diagnostic and/or prognostic biomarkers. Finally, we discuss the unmet needs that researchers should tackle to advance in the knowledge of these barely explored pathologies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.