ArticleFoods (Basel, Switzerland)2021
Analysis of the Endogenous Peptidomes of Different Infant Formula Types and Human Milk.
Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Peptidomic Profiling Analysis of Endogenous Peptides in Buffalo Milk During Lactation Stages.Foods (Basel, Switzerland) · 2026Article
- Evaluation of UHT milk spoilage caused by proteases from psychrophilic bacteria based on peptidomics.Food chemistry: X · 2024Article
- High-Temperature, Solid-Phase Reaction of α-Amino Groups in Peptides with Lactose and Glucose: An Alternative Mechanism Leading to an α-Ketoacyl Derivative.Journal of agricultural and food chemistry · 2023Article
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Authors and funding
4 authors.
Funding
Abstract
Infant formula (IF) is a commonly used replacement whenever mother's own milk is not available. Most IFs are based on cow milk (powders, liquids). Alternatives, based on other sources such as goat milk or plants, exist. Independent of the source, IF production and composition are strictly regulated. Besides proteins, minerals, and lipids, milk contains a variety of endogenous peptides. Whereas the human milk peptidome has been studied intensively, the peptidomes of IFs have been mostly neglected. This study investigated the peptidomes of different types of first stage IF, including cow milk-based powders and liquids, and powdered goat milk-based IF, highlighting major similarities and differences to human milk. Extracted native peptidomes were analyzed by nanoRPC-ESI-MS/MS using two different fragmentation techniques allowing the confident identification of 1587 peptides. β-Casein peptides dominated in all samples. Interestingly, powdered and liquid cow milk-based IFs differed in the numbers of β- and α
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