Evidence map›Paper›PMID 34828760›Full record

ArticleChildren (Basel, Switzerland)2021

Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia.

Alina Ofenheimer, Robab Breyer-Kohansal, Sylvia Hartl, Otto C Burghuber, Florian Krach, Frits M E Franssen, Emiel F M Wouters, Marie-Kathrin Breyer

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Alina OfenheimerLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.ORCID 0000-0002-3698-9805
Robab Breyer-KohansalLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.
Sylvia HartlLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.
Otto C BurghuberLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.
Florian KrachDepartment of Mathematics, ETH Zürich, 8092 Zurich, Switzerland.ORCID 0000-0001-7478-8361
Frits M E FranssenNUTRIM, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-1633-6356
Emiel F M WoutersLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.
Marie-Kathrin BreyerLudwig Boltzmann Institute for Lung Health, 1140 Vienna, Austria.
University Medical Center · USLudwig Boltzmann Institute for Lung Vascular Research · ATSigmund Freud Privatuniversität Wien · ATETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of body composition on the early origin of chronic diseases is an increasingly appreciated phenomenon. Little is known about the characteristics of children with varying body composition. The aim of this study was to investigate serum lipid profiles and other characteristics in relation to body composition. The data of 1394 participants (aged 6 to <18 years) of the observational general population-based Austrian LEAD Study have been analyzed. Body composition groups were defined by appendicular lean mass (ALMI) and fat mass (FMI) indices assessed by DXA. Serum lipid profiles (triglycerides, LDL-c, HDL-c) and other characteristics (e.g., prematurity, smoke exposure, physical activity, nutrition) were investigated in these body composition groups. Different body composition groups, which are not distinguishable by BMI, exist. Children with high ALMI and high FMI showed higher triglycerides and LDL-c, but lower HDL-c levels. In contrast, levels did not differ between those with high FMI but low (or normal) ALMI, and other body composition groups. BMI should be interpreted cautiously, and body composition should be measured by more precise techniques. In particular, children and adolescents with high FMI who have concomitantly high ALMI should be followed closely in future studies to investigate whether they are at increased risk of cardiovascular problems.

Indexed as

body compartmentsbody compositioncardiovascular riskdyslipidemiamuscle massphysical activity

Identifiers

PMID34828760
PMCPMC8625256
OpenAlexW3212601733

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.