Evidence map›Paper›PMID 34828678›Full record

ArticleChildren (Basel, Switzerland)2021

Opsoclonus-Myoclonus Syndrome in Children and Adolescents: A Therapeutic Challenge.

Marina Auconi, Laura Papetti, Claudia Ruscitto, Michela Ada Noris Ferilli, Fabiana Ursitti, Giorgia Sforza, Federico Vigevano, Massimiliano Valeriani

Abstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Opsoclonus Myoclonus Ataxia Syndrome: An Atypical Presentation of Tuberculous Meningitis.The American journal of tropical medicine and hygiene · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marina AuconiChild Neurology and Psychiatry Unit, Systems Medicine Department, Tor Vergata University of Rome, 00133 Rome, Italy.
Laura PapettiChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Claudia RuscittoChild Neurology and Psychiatry Unit, Systems Medicine Department, Tor Vergata University of Rome, 00133 Rome, Italy.
Michela Ada Noris FerilliChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Fabiana UrsittiChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Giorgia SforzaChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Federico VigevanoChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Massimiliano ValerianiChild Neurology Unit, Neuroscience Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-6602-103X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opsoclonus-myoclonus syndrome (OMS) is a neurological non-fatal disease that usually responds to immunotherapies. However, the real challenge is to counteract the high frequency of relapses and long-term developmental sequelae. Since the OMS is extremely rare, a common consensus regarding therapeutic guidelines is still lacking. The goals of this study were to test whether ACTH was superior to other immunotherapies and to investigate whether an early treatment could improve the outcome. Sixteen children affected by OMS were retrospectively reviewed. Eight children had a neuroblastic tumor. The other eight patients were affected by non-paraneoplastic OMS. Overall, the most commonly used treatment was corticotherapy (

Indexed as

childrenneuroblastic tumorsopsoclonus-myoclonus syndromeoutcomepediatric neuroimmunological disordertreatment

Identifiers

PMID34828678
PMCPMC8625142

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.