Evidence map›Paper›PMID 34828664›Full record

ArticleChildren (Basel, Switzerland)2021

COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes.

Sara Rubenstein, Emily Grew, Katharine Clouser, Alexander Kwok, Aravindhan Veerapandiyan, Jeffrey Kornitzer, Keith Pecor, Xue Ming

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sara RubensteinDepartment of Neurology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Emily GrewDepartment of Neurology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.ORCID 0000-0001-7094-1234
Katharine ClouserPediatric Hospital Medicine, Hackensack University Medical Center, Hackensack, NJ 07601, USA.
Alexander KwokDivision of Pediatric Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72005, USA.
Aravindhan VeerapandiyanDivision of Pediatric Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72005, USA.ORCID 0000-0002-3065-3956
Jeffrey KornitzerDepartment of Neurology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Keith PecorDepartment of Biology, The College of New Jersey, Ewing, NJ 08628, USA.
Xue MingDepartment of Neurology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.ORCID 0000-0003-0752-5777
Rutgers, The State University of New Jersey · USUniversity of Arkansas for Medical Sciences · USCollege of New Jersey · USHackensack University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term outcomes of COVID-19 in 82 pediatric patients at three hospitals within the United States during the spring and summer of 2020 using medical records, laboratory data, and imaging studies of all patients admitted with a positive RT-PCR test for SARS-CoV-2. We found that older patients were more likely to have an extended hospital stay, and those with high BMIs (over 25) were more likely to be admitted to the PICU during the early pandemic. In addition, older patients, those with high BMIs, and those with underlying medical conditions, were more likely to receive respiratory support. Given the association of age, BMI, and underlying medical conditions with more severe COVID-19, clinicians should keep these factors in mind when treating patients.

Indexed as

agebody mass indexCOVID-19pediatric intensive care unitrespiratory support

Identifiers

PMID34828664
PMCPMC8620202
OpenAlexW3210082578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.