Evidence map›Paper›PMID 34828659›Full record

ArticleChildren (Basel, Switzerland)2021

Genetic Variants of DMBT1 and SFTPD and Disease Severity in Paediatric Inflammatory Bowel Disease-A Polish Population-Based Study.

Aleksandra Glapa-Nowak, Mariusz Szczepanik, Aleksandra Banaszkiewicz, Barbara Iwańczak, Jarosław Kwiecień, Anna Szaflarska-Popławska, Urszula Grzybowska-Chlebowczyk, Marcin Osiecki, Jarosław Kierkuś, Marcin Banasiuk and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Aleksandra Glapa-NowakDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, 60-572 Poznan, Poland.ORCID 0000-0002-3017-0524
Mariusz SzczepanikDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, 60-572 Poznan, Poland.
Aleksandra BanaszkiewiczDepartment of Pediatric Gastroenterology and Nutrition, Medical University of Warsaw, 02-091 Warszawa, Poland.
Barbara IwańczakDepartment and Clinic of Pediatrics, Gastroenterology and Nutrition, Wroclaw Medical University, 50-367 Wrocław, Poland.
Jarosław KwiecieńDepartment of Pediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0002-6764-8261
Anna Szaflarska-PopławskaDepartment of Pediatric Endoscopy and Gastrointestinal Function Testing, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland.
Urszula Grzybowska-ChlebowczykDepartment of Pediatrics, Faculty of Medical Sciences, Medical University of Silesia, 40-752 Katowice, Poland.
Marcin OsieckiThe Department of Gastroenterology, Hepatology, Feeding Disorders and Paediatrics, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.ORCID 0000-0002-4765-7849
Jarosław KierkuśThe Department of Gastroenterology, Hepatology, Feeding Disorders and Paediatrics, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Marcin BanasiukDepartment of Pediatric Gastroenterology and Nutrition, Medical University of Warsaw, 02-091 Warszawa, Poland.
Tomasz BanasiewiczChair and Department of General Surgery, Gastroenterological Surgical Oncology and Plastic Surgery, Poznań University of Medical Sciences, 60-572 Poznan, Poland.
Jens MadsenThe Elizabeth Garrett Anderson Institute for Women's Health, Faculty of Population Health Sciences, University College London, London 84-86, UK.
Jarosław WalkowiakDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, 60-572 Poznan, Poland.ORCID 0000-0001-5813-5707
Poznan University of Medical Sciences · PLChildren's Memorial Health Institute · PLMedical University of Silesia · PLMedical University of Warsaw · PLNicolaus Copernicus University · PLUniversity College Hospital · GBWroclaw Medical University · PL

Funding

National Science Center 2017/25/B/NZ5/02783
6 · The paper itself

Abstract

Deleted in malignant brain tumours 1 protein (DMBT1) and surfactant protein D (SFTPD) are antimicrobial peptides previously linked to inflammatory bowel disease (IBD) susceptibility. This study attempts to link the most potential IBD-associated polymorphisms in DMBT1 and SFTPD with the disease severity in children. A total of 406 IBD patients (Crohn's disease (CD)

Indexed as

Crohn’s diseaseexacerbationhospitalisationimmunosuppressionpolymorphismrelapseulcerative colitis

Identifiers

PMID34828659
PMCPMC8618964
OpenAlexW3207273397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.