Evidence map›Paper›PMID 34828637›Full record

ArticleHealthcare (Basel, Switzerland)2021

Nanostring-Based Identification of the Gene Expression Profile in Trigger Finger Samples.

Ravindra Kolhe, Umar Ghilzai, Ashis K Mondal, Chetan Pundkar, Pankaj Ahluwalia, Nikhil S Sahajpal, Jie Chen, Carlos M Isales, Mark Fulcher, Sadanand Fulzele

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ravindra KolheDepartment of Pathology, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-8283-2403
Umar GhilzaiDepartment of Orthopedics, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0003-2207-074X
Ashis K MondalDepartment of Pathology, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0003-3826-9489
Chetan PundkarDepartment of Pathology, Auburn University, Auburn, AL 36849, USA.
Pankaj AhluwaliaDepartment of Pathology, Augusta University, Augusta, GA 30912, USA.
Nikhil S SahajpalDepartment of Pathology, Augusta University, Augusta, GA 30912, USA.
Jie ChenDivision of Biostatistics & Data Sciences, DPHS, Augusta University, Augusta, GA 30912, USA.
Carlos M IsalesCenter for Healthy Aging, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-4480-3484
Mark FulcherDepartment of Orthopedics, Augusta University, Augusta, GA 30912, USA.
Sadanand FulzeleDepartment of Orthopedics, Augusta University, Augusta, GA 30912, USA.
Augusta University · USAuburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trigger finger is a common yet vastly understudied fibroproliferative hand pathology, severely affecting patients' quality of life. Consistent trauma due to inadequate positioning within the afflicted finger's tendon/pulley system leads to cellular dysregulation and eventual fibrosis. While the genetic characteristics of the fibrotic tissue in the trigger finger have been studied, the pathways that govern the initiation and propagation of fibrosis are still unknown. The complete gene expression profile of the trigger finger has never been explored. Our study has used the Nanostring nCounter gene expression assay to investigate the molecular signaling involved in trigger finger pathogenesis. We collected samples from patients undergoing trigger finger (

Indexed as

gene expressionNanostringpaintrigger finger

Identifiers

PMID34828637
PMCPMC8619339
OpenAlexW3217613983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.