Evidence map›Paper›PMID 34828498›Full record

ArticleHealthcare (Basel, Switzerland)2021

Bone Marrow Hypocellularity in Patients with End-Stage Kidney Disease.

Chia-Chen Hsieh, Ming-Jen Chan, Yi-Jiun Su, Jen-Fen Fu, I-Kuan Wang, Chao-Yu Chen, Cheng-Hao Weng, Wen-Hung Huang, Ching-Wei Hsu, Tzung-Hai Yen

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Review
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chia-Chen HsiehClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Ming-Jen ChanClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.ORCID 0000-0003-1482-8557
Yi-Jiun SuDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Jen-Fen FuCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
I-Kuan WangDepartment of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Chao-Yu ChenClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Cheng-Hao WengClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Wen-Hung HuangClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Ching-Wei HsuClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.
Tzung-Hai YenClinical Poison Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.ORCID 0000-0002-0907-1505
Chang Gung University · TWChang Gung Memorial Hospital · TWChina Medical University · TW

Funding

Chang Gung Memorial Hospital CORPG3K0192, CMRPG3J1053, CORPG3L0291
6 · The paper itself

Abstract

backgroundAnemia and pancytopenia are not uncommon in patients with chronic kidney disease (CKD). Nevertheless, there is insufficient literature analyzing bone marrow pathology in patients with CKD or end-stage kidney disease (ESKD) receiving dialysis.

methodsThis observational cohort study included 22 patients with ESKD and 23 patients with CKD that received bone marrow biopsy and aspiration at Chang Gung Memorial Hospital. Demographic, hematological, and biochemical data were collected at the time of bone marrow study for analysis.

resultsBone marrow aspiration demonstrated that patients with ESKD had a lower percentage of blasts than patients with CKD (0.52 ± 0.84 versus 1.06 ± 0.78 %,

conclusionBone marrow hypocellularity is common in patients with kidney dysfunction. Hypocellular marrow occurs more frequently in patients with ESKD than patients with CKD.

Indexed as

biopsybone marrowchronic kidney diseaseend-stage kidney diseasehypocellularity

Identifiers

PMID34828498
PMCPMC8621268
OpenAlexW3210487642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.