Evidence map›Paper›PMID 34828476›Full record

ReviewHealthcare (Basel, Switzerland)2021

Virtual Reality Rehabilitation's Impact on Negative Symptoms and Psychosocial Rehabilitation in Schizophrenia Spectrum Disorder: A Systematic Review.

André Novo, Jéssica Fonsêca, Bárbara Barroso, Manuel Guimarães, Afonso Louro, Hélder Fernandes, Rui Pedro Lopes, Paulo Leitão

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. A scoping review of the nature and extent of the use of storytelling as a component of oral health education.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

André NovoCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.ORCID 0000-0001-8583-0406
Jéssica FonsêcaCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.ORCID 0000-0001-8609-3575
Bárbara BarrosoCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.
Manuel GuimarãesCampus de Santa Apolónia, Research Center in Digitalization and Intelligent Robotics (CeDRI), 5300-253 Bragança, Portugal.
Afonso LouroAvenida Abade de Baçal, Mental Health Department, Unidade Local de Saúde do Nordeste, 5301-852 Bragança, Portugal.
Hélder FernandesCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.
Rui Pedro LopesCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.ORCID 0000-0002-9170-5078
Paulo LeitãoCampus de Santa Apolónia, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.ORCID 0000-0002-2151-7944
Polytechnic Institute of Bragança · PTUnidade Hospitalar de Bragança · PT

Funding

European Regional Development Fund Norte-01-0145-FEDER-000042.
6 · The paper itself

Abstract

backgroundSchizophrenia is a chronic psychiatric disorder with symptoms that can severely affect patients' quality of life. While drug administration inhibits most of the positive symptoms, it fails to effectively treat the negative symptoms and in turn relies on rehabilitation therapies. With technological progress, virtual reality (VR) has been the target of recent studies in terms of mental health rehabilitation and has been shown to be a tool with ecological validity in order to introduce the individual to situations similar to their daily life.

methodsFrom July to August 2021, we conducted a systematic review with the purpose of understanding the impact of virtual reality rehabilitation on negative symptoms and psychosocial rehabilitation in the schizophrenia spectrum. The searches were performed in the databases Web of Science, Scopus, and PubMed.

resultsIn our search, we identified 201 results, where 108 duplicates were excluded, resulting in a final balance of 93. After reading and assessing the titles and abstracts, 66 studies were excluded. Of the remaining 27 reports, 23 were excluded for not meeting the previously defined eligibility criteria, resulting in the inclusion of four studies in this systematic review.

conclusionsThe available data on the specific topic was limited and could have been more complete. However, in our review, we were able to identify statistically relevant results demonstrating the effectiveness of intervention. We could find medium to large effects, allowing VR to be an ally for rehabilitation of symptoms related to schizophrenia.

Indexed as

schizophreniaserious gamevirtual realityvirtual reality exposure therapy

Identifiers

PMID34828476
PMCPMC8621037
OpenAlexW3210253878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.