Evidence map›Paper›PMID 34828287›Full record

ReviewGenes2021

Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes.

Olga V Balberova, Evgeny V Bykov, German V Medvedev, Margarita A Zhogina, Kirill V Petrov, Marina M Petrova, Mustafa Al-Zamil, Vera V Trefilova, Polina S Goncharova, Natalia A Shnayder

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Olga V BalberovaThe Research Institute of Olympic Sports, Ural State University of Physical Culture, 454091 Chelyabinsk, Russia.ORCID 0000-0001-5513-6384
Evgeny V BykovThe Research Institute of Olympic Sports, Ural State University of Physical Culture, 454091 Chelyabinsk, Russia.
German V MedvedevDepartment of Hand Surgery with Microsurgical Equipment, Vreden National Medical Research Center of Traumatology and Orthopedics, 195427 St. Petersburg, Russia.
Margarita A ZhoginaDepartment of Hand Surgery with Microsurgical Equipment, Vreden National Medical Research Center of Traumatology and Orthopedics, 195427 St. Petersburg, Russia.ORCID 0000-0001-8825-8222
Kirill V PetrovDepartment of Physical and Rehabilitation Medicine with a Postgraduate Course, Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.
Marina M PetrovaDepartment of Physical and Rehabilitation Medicine with a Postgraduate Course, Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.
Mustafa Al-ZamilDepartment of Physiotherapy, Peoples' Friendship University of Russia, 117198 Moscow, Russia.
Vera V TrefilovaThe Neurological Department No. 16, The Hospital for War Veterans, 193079 St. Petersburg, Russia.
Polina S GoncharovaCenter of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Center for Psychiatry Neurology, 192019 St. Petersburg, Russia.
Natalia A ShnayderCenter of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Center for Psychiatry Neurology, 192019 St. Petersburg, Russia.ORCID 0000-0002-2840-837X
Krasnoyarsk State Medical University · RURussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden · RUSt.Petersburg V.M.Bekhterev Psychoneurological Research Institute · RUUral State University of Physical Culture · RUPeoples' Friendship University of Russia · RUSt. Petersburg State Medical Academy "City Hospital No. 26" · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignorance of these features can create genetic "barriers" that prevent professional athletes from pursuing a career in sports. Predictive Genomic DNA Profiling reveals single nucleotide variations (SNV) that may be associated with better suitability for endurance, strength and speed sports. (1) Background: To conduct a research on candidate genes associated with regulation of skeletal muscle energy metabolism among athletes. (2) Methods: We have searched for articles in SCOPUS, Web of Science, Google Scholar, Clinical keys, PubMed, e-LIBRARY databases for the period of 2010-2020 using keywords and keywords combinations; (4) Conclusions: Identification of genetic markers associated with the regulation of energy metabolism in skeletal muscles can help sports physicians and coaches develop personalized strategies for selecting children, teenagers and young adults for endurance, strength and speed sports (such as jogging, middle or long distance runs). However, the multifactorial aspect of sport performances, including impact of genetics, epigenetics, environment (training and etc.), is important for personalized strategies for selecting of athletes. This approach could improve sports performance and reduce the risk of sports injuries to the musculoskeletal system.

Indexed as

Athletic PerformanceGenetic MarkersAthletesEnergy MetabolismEpigenesis, GeneticGene Expression RegulationHumansMuscle, SkeletalPolymorphism, Single NucleotidePrecision MedicineGenetic Markersathletecandidate genesenergy metabolismpersonalized medicinepolymorphismsingle nucleotide variantskeletal musclessports genetics

Identifiers

PMID34828287
PMCPMC8625318
OpenAlexW3210580852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.