ReviewAnimals : an open access journal from MDPI2021
Toxic Effects on Bioaccumulation, Hematological Parameters, Oxidative Stress, Immune Responses and Tissue Structure in Fish Exposed to Ammonia Nitrogen: A Review.
Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 237 citations in OpenAlex.
- The price of protection: an integrated toxicological and modelling assessment of flubendiamide exposure in Anabas testudineus.Fish physiology and biochemistry · 2026Article
- Corn husk meal as a sustainable dietary additive in biofloc-cultured koi carp (Cyprinus carpio var. koi): Integrative effects on growth performance, immune response, histology, gene expression, and ammonia-stress resilience.Veterinary research communications · 2026Article
- Multi-Omics Analysis of Hepatopancreatic Responses to Ammonia Nitrogen Stress in Diploid Pacific Oysters (Animals : an open access journal from MDPI · 2026Article
- Hesperidin dietary intervention mitigates ammonia stress-evoked biochemical and metabolic disruption and restores the tlr-5-nf-κβ/mapk gene expression in Oreochromis niloticus.Fish physiology and biochemistry · 2026Article
- Underlying the Enhanced Ammonia Stress Resistance by Prebiotic Xylo-Oligosaccharides in Hybrid Groupers: An Integrative Analysis of Serum Physiology, Hepatic Transcriptomics, and Intestinal Health.Animals : an open access journal from MDPI · 2026Article
- Multi-Tissue Transcriptomics Analysis of the Effects of Ammonia Nitrogen Stress on Metabolism, Immunity, and Comprehensive Stress Responses inAnimals : an open access journal from MDPI · 2026Article
- Effects of Stocking Density and Body Size on Oxygen Consumption and Ammonia Excretion in Silverside (Animals : an open access journal from MDPI · 2026Article
- Effects of Ascorbic Acid on Apoptosis, Metabolism, and Muscle Quality in Ammonia-Stressed Rainbow Trout (Foods (Basel, Switzerland) · 2026Article
- Article
- Mechanistic approach on the protective role of rutin against ammonia-induced hepatic encephalopathy in Nile tilapia (Oreochromis niloticus) focusing on Cox-2/NF-κB pathway.Fish physiology and biochemistry · 2026Article
- Amelioration of ammonia-induced oxidative stress, ferroptosis and intestinal damage in Pelteobagrus fulvidraco through dietary tea polyphenols.Journal of fish biology · 2026Article
- Effects of Dietary Host-DerivedAnimals : an open access journal from MDPI · 2026Article
- The Role of Thioredoxin in Mitigating Ammonia-Induced Oxidative Stress in Nile Tilapia (Animals : an open access journal from MDPI · 2026Article
- Ammonia stress induces hepatotoxicity in hybrid grouper: histological, oxidative, inflammatory, and metabolomic responses.Fish physiology and biochemistry · 2026Article
- Effects of iron and silver nanoparticles on Ctenopharyngodon idella's swimming performance, their bioaccumulation, histological changes, and oxidative stress.Discover nano · 2026Article
- Enhanced Nitrification in Yellow Clay Improves In Situ Water Purification for Eel Aquaculture: A Preliminary Assessment.Microorganisms · 2026Article
- Dietary rutin enhances growth performance and antioxidant defense under ammonia stress in Nile tilapia (Oreochromis Niloticus).Veterinary research communications · 2026Article
- Acute Total Ammonia Nitrogen (TAN) stress affects the skin metabolism, antioxidant capacity, immune function, and tissue structure of juvenile yellowfin tuna (Thunnus albacares).Fish physiology and biochemistry · 2026Article
- Response of epithelial cell lines from the rainbow trout gut and gill to ammonia.In vitro cellular & developmental biology. Animal · 2026Article
- Short-term acclimation at elevated temperatures alters hematobiochemical parameters, erythrocyte and muscle structure, and critical thermal tolerance (CTmax) limit of Nile tilapia, Oreochromis niloticus.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Ammonia nitrogen is the major oxygen-consuming pollutant in aquatic environments. Exposure to ammonia nitrogen in the aquatic environment can lead to bioaccumulation in fish, and the ammonia nitrogen concentration is the main determinant of accumulation. In most aquatic environments, fish are at the top of the food chain and are most vulnerable to the toxic effects of high levels of ammonia nitrogen exposure. In fish exposed to toxicants, ammonia-induced toxicity is mainly caused by bioaccumulation in certain tissues. Ammonia nitrogen absorbed in the fish enters the circulatory system and affects hematological properties. Ammonia nitrogen also breaks balance in antioxidant capacity and causes oxidative damage. In addition, ammonia nitrogen affects the immune response and causes neurotoxicity because of the physical and chemical toxicity. Thence, the purpose of this review was to investigate various toxic effects of ammonia nitrogen, including oxidative stress, neurotoxicity and immune response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.