Evidence map›Paper›PMID 34827925›Full record

ArticleAnimals : an open access journal from MDPI2021

Integration of Microfluidics, Photonic Integrated Circuits and Data Acquisition and Analysis Methods in a Single Platform for the Detection of Swine Viral Diseases.

Georgios Manessis, Christos Mourouzis, Amadeu Griol, David Zurita-Herranz, Sergio Peransi, Carlos Sanchez, Alessandro Giusti, Athanasios I Gelasakis, Ioannis Bossis

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. SPR-Based Detection of ASF Virus in Cells.International journal of molecular sciences · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Georgios ManessisLaboratory of Anatomy and Physiology of Farm Animals, Department of Animal Science, Agricultural University of Athens (AUA), Iera Odos 75 Str., 11855 Athens, Greece.ORCID 0000-0002-0025-9288
Christos MourouzisCyRIC, Cyprus Research and Innovation Centre Ltd., 28th Octovriou Ave 72, Off. 301, Engomi, Nicosia 2414, Cyprus.ORCID 0000-0001-8365-4605
Amadeu GriolNanophotonics Technology Center, Universitat Politècnica de València, Camino de Vera s/n Building 8F, 46022 Valencia, Spain.ORCID 0000-0002-5428-5713
David Zurita-HerranzNanophotonics Technology Center, Universitat Politècnica de València, Camino de Vera s/n Building 8F, 46022 Valencia, Spain.
Sergio PeransiLumensia Sensors S.L., Camino de Vera, s/n, K-Access, Building 8F 3th-Floor, 46022 Valencia, Spain.
Carlos SanchezLumensia Sensors S.L., Camino de Vera, s/n, K-Access, Building 8F 3th-Floor, 46022 Valencia, Spain.
Alessandro GiustiCyRIC, Cyprus Research and Innovation Centre Ltd., 28th Octovriou Ave 72, Off. 301, Engomi, Nicosia 2414, Cyprus.ORCID 0000-0002-6803-3795
Athanasios I GelasakisLaboratory of Anatomy and Physiology of Farm Animals, Department of Animal Science, Agricultural University of Athens (AUA), Iera Odos 75 Str., 11855 Athens, Greece.ORCID 0000-0003-1144-3918
Ioannis BossisLaboratory of Animal Husbandry, Department of Animal Production, School of Agriculture, Faculty of Agriculture, Forestry and Natural Environment, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Agricultural University of Athens · GRCyprus Research and Innovation Center (Cyprus) · CYUniversitat Politècnica de València · ESAristotle University of Thessaloniki · GR

Funding

Horizon 2020, the EU Framework Programme for Research and Innovation for 2014-2020 under grant agreement No 771649. 771649
6 · The paper itself

Abstract

Viral diseases challenge the health and welfare of pigs and undermine the sustainability of swine farms. Their efficient control requires early and reliable diagnosis, highlighting the importance of Point of Care (POC) diagnostics in veterinary practice. The objective of this study was to validate a novel POC system that utilizes Photonic Integrated Circuits (PICs) and microfluidics to detect swine viral pathogens using oral fluids and Porcine Parvovirus (PPV) and Porcine Circovirus 2 (PCV-2) as proofs of concept. The sensitivity and specificity of the device were calculated for both viruses, and Receiver Operating Characteristic (ROC) curves were drawn. PPV had an Area Under Curve (AUC) value of 0.820 (95% CI: 0.760 to 0.880,

Indexed as

diagnosticsmicrofluidicsoral fluidsPhotonic Integrated Circuits (PICs)Point of Care (POC)Porcine Circovirus 2 (PCV-2)Porcine Parvovirus (PPV)validation

Identifiers

PMID34827925
PMCPMC8614420
OpenAlexW3211474549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.