Evidence map›Paper›PMID 34827885›Full record

ArticleAnimals : an open access journal from MDPI2021

Effect of Heat Stress on Bovine Mammary Cellular Metabolites and Gene Transcription Related to Amino Acid Metabolism, Amino Acid Transportation and Mammalian Target of Rapamycin (mTOR) Signaling.

Lin Fu, Li Zhang, Li Liu, Heng Yang, Peng Zhou, Fan Song, Guozhong Dong, Juncai Chen, Gaofu Wang, Xianwen Dong

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lin FuChongqing Academy of Animal Sciences, Chongqing 402460, China.
Li ZhangChongqing Academy of Animal Sciences, Chongqing 402460, China.
Li LiuFaculty of Pharmaceutical Engineering, Chongqing Chemical Industry Vocational College, Chongqing 401228, China.
Heng YangCollege of Veterinary Medicine, Southwest University, Chongqing 402460, China.
Peng ZhouChongqing Academy of Animal Sciences, Chongqing 402460, China.
Fan SongChongqing Academy of Animal Sciences, Chongqing 402460, China.
Guozhong DongCollege of Animal Science and Technology, Southwest University, Chongqing 400716, China.ORCID 0000-0001-7355-3050
Juncai ChenCollege of Animal Science and Technology, Southwest University, Chongqing 400716, China.
Gaofu WangChongqing Academy of Animal Sciences, Chongqing 402460, China.
Xianwen DongChongqing Academy of Animal Sciences, Chongqing 402460, China.
Chongqing Academy of Animal Science · CNSouthwest University · CNChongqing Medical and Pharmaceutical College · CN

Funding

Chongqing Postdoctoral Science Special Foundation XmT2018001Natural Science Foundation of Chongqing cstc2020jcyj-msxmX0481
6 · The paper itself

Abstract

Heat stress (HS) is one of the most serious factors to negatively affect the lactation performance of dairy cows. Bovine mammary epithelial cells are important for lactation. It was demonstrated that HS decreases the lactation performance of dairy cows, partly through altering gene expression within bovine mammary epithelial tissue. However, the cellular metabolism mechanisms under HS remains largely unknown. The objective of this study was to determine whether HS induced changes in intracellular metabolites and gene transcription related to amino acid metabolism, amino acid transportation and the mTOR signaling pathway. Immortalized bovine mammary epithelial cell lines (MAC-T cells,

Indexed as

amino acid metabolismheat stressMAC-T cellmetabolomicsmilk protein synthesis

Identifiers

PMID34827885
PMCPMC8614368
OpenAlexW3210502328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.