Evidence map›Paper›PMID 34827867›Full record

ArticleAnimals : an open access journal from MDPI2021

In Vitro Studies on the Influence of Meloxicam on Cytotoxic Activity Induced by Risedronate Sodium in Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines.

Dominik Poradowski, Izabela Janus, Aleksander Chrószcz, Bożena Obmińska-Mrukowicz

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dominik PoradowskiDepartment of Animal Physiology and Biostructure, Division of Animal Anatomy, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Kożuchowska 1, 51-631 Wrocław, Poland.ORCID 0000-0003-4296-3174
Izabela JanusDepartment of Pathology, Division of Pathomorphology and Veterinary Forensics, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, C. K. Norwida 31, 50-375 Wrocław, Poland.ORCID 0000-0001-5166-856X
Aleksander ChrószczDepartment of Animal Physiology and Biostructure, Division of Animal Anatomy, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Kożuchowska 1, 51-631 Wrocław, Poland.ORCID 0000-0001-9079-549X
Bożena Obmińska-MrukowiczDepartment of Pharmacology and Toxicology, Division of Pharmacology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, C. K. Norwida 31, 50-375 Wrocław, Poland.
Wrocław University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study describes the cytotoxic effect against human and canine osteosarcoma (U-2 OS and D-17) cell lines induced by risedronate sodium and meloxicam per se and in combination. Both cell lines were prepared according to standard procedures for cell cultures studies. The cell viability was estimated in both cell lines treated with chosen concentrations of risedronate sodium and meloxicam. The apoptosis assessment was carried out using TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assay. EC

Indexed as

caninehumaninteractionmeloxicamosteosarcomarisedronate sodium

Identifiers

PMID34827867
PMCPMC8614298
OpenAlexW3209640708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.