Evidence map›Paper›PMID 34827849›Full record

ArticleAnimals : an open access journal from MDPI2021

The Distribution, Expression Patterns and Functional Analysis of NR1D1 and NR4A2 in the Reproductive Axis Tissues of the Male Tianzhu White Yak.

Lijun Dai, Quanwei Zhang, Jun Shi, Xu Bai, Xiaoxiao An, Bohao Zhang, Yong Zhang, Xingxu Zhao

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Exploring the Mechanism of HInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lijun DaiCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Quanwei ZhangCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0002-5476-508X
Jun ShiCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Xu BaiCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Xiaoxiao AnCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Bohao ZhangGansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Lanzhou 730070, China.
Yong ZhangCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Xingxu ZhaoCollege of Life Science and Biotechnology, Gansu Agricultural University, Lanzhou 730070, China.
Gansu Agricultural University · CN

Funding

National Natural Science Foundation of China No.32060752the Innovation Ability and Improvement Project of Higher Education Department of Gansu Province, China 2019A-049
6 · The paper itself

Abstract

Nuclear hormone receptors NR1D1 and NR4A2 play important roles in the synthesis and metabolism of hormones that are thought to be strictly regulated by the hypothalamus-pituitary-gonad axis (HPG) tissues via gene expression. However, in the yak, the function and regulatory mechanisms of NR1D1 and NR4A2 are not clearly understood. The current study is aimed to investigate the expression patterns, distribution and functions of these two receptors in HPG tissues in male Tianzhu white yaks. Immunohistochemical staining showed NR1D1 and NR4A2 proteins were present in all yak HPG tissues with differential expression patterns and degrees of staining, particularly in Leydig cells that were strongly positive in accordance with the immunofluorescence results. qRT-PCR and Western blot results suggested that the highest expression levels of

Indexed as

NR1D1NR4A2reproduction axissterol hormoneyak

Identifiers

PMID34827849
PMCPMC8614427
OpenAlexW3208248853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.