Evidence map›Paper›PMID 34827708›Full record

ArticleBiomolecules2021

Engineering of

Jiao Yang, Changfu Li, Yansheng Zhang

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Enhancing Withanolide Production in thePlants (Basel, Switzerland) · 2024
    Review
  6. Advances inFrontiers in plant science · 2024
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiao YangSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.ORCID 0000-0002-5475-8525
Changfu LiSchool of Life Sciences, Shanghai University, Shanghai 200444, China.
Yansheng ZhangSchool of Life Sciences, Shanghai University, Shanghai 200444, China.ORCID 0000-0001-7597-9821
Shanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

24-Methylene-cholesterol is a necessary substrate for the biosynthesis of physalin and withanolide, which show promising anticancer activities. It is difficult and costly to prepare 24-methylene-cholesterol via total chemical synthesis. In this study, we engineered the biosynthesis of 24-methylene-cholesterol in

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAnimalsCholesterolCytochrome P-450 Enzyme SystemMetabolic EngineeringOxidoreductases Acting on CH-CH Group Donors7-dehydrocholesterol reductaseCholesterolCytochrome P-450 Enzyme SystemERG5 protein, S cerevisiaeOxidoreductases Acting on CH-CH Group DonorsSaccharomyces cerevisiae Proteins24-methylene-cholesterol7-dehydrocholesterol reductasecampesterol

Identifiers

PMID34827708
PMCPMC8615579
OpenAlexW3214402866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.