Evidence map›Paper›PMID 34827563›Full record

ArticleBiomolecules2021

Novel Structures of Type 1 Glyceraldehyde-3-phosphate Dehydrogenase from

Li Zhang, Meiruo Liu, Luyao Bao, Kristina I Boström, Yucheng Yao, Jixi Li, Shaohua Gu, Chaoneng Ji

Abstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li ZhangState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0003-2638-2919
Meiruo LiuState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.
Luyao BaoState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.
Kristina I BoströmDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Yucheng YaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Jixi LiState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0003-3463-3175
Shaohua GuState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.
Chaoneng JiState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-5457-5067

Funding

Molecular Mechanisms of MGP; Role in AVMsR01HL081397 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOSTROM, KRISTINA I · 2006 to 2025
$7.7M
BMP and Notch Crosstalk in Cerebral Arteriovenous MalformationsR01NS079353 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2012 to 2026
$5.3M
Switch of Osteogenesis in Vascular CalcificationR01HL139675 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2018 to 2026
$3.6M
Endothelial Regulation of Vascular CalcificationR01HL158053 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOSTROM, KRISTINA I · 2022 to 2025
$2.2M
NHLBI NIH HHS R01 HL081397NHLBI NIH HHS R01 HL139675NHLBI NIH HHS R01 HL158053NINDS NIH HHS R01 NS079353
6 · The paper itself

Abstract

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme involved in the ubiquitous process of glycolysis and presents a loop (residues 208-215 of

Indexed as

Escherichia coliGlyceraldehyde-3-Phosphate DehydrogenasesCrystallography, X-RayDiphosphoglyceric AcidsEscherichia coli ProteinsModels, MolecularNADProtein ConformationDiphosphoglyceric AcidsEscherichia coli ProteinsGlyceraldehyde-3-Phosphate DehydrogenasesNAD1,3-diphosphoglycerateBPGcatalytic processEscherichia coli type 1 GAPDHthioacyl intermediate structure

Identifiers

PMID34827563
PMCPMC8615399

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.