ArticleBrain sciences2021
Relationship between Amyloid-β Deposition and the Coupling between Structural and Functional Brain Networks in Patients with Mild Cognitive Impairment and Alzheimer's Disease.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Decreased amyloid-related structure-function coupling in preclinical Alzheimer's disease.Communications medicine · 2026Article
- Multimodal non-invasive approaches for early Alzheimer's disease detection: a review of neuroelectrophysiological and neuroimaging techniques.Frontiers in psychiatry · 2026Review
- The structural grammar of integration and competition in the human connectome.Frontiers in computational neuroscience · 2026Article
- Amyloid pathology related to aberrant structure-function coupling of brain networks in Alzheimer's disease: insights from [European journal of nuclear medicine and molecular imaging · 2025Article
- Detection of Alzheimer's disease onset using MRI and PET neuroimaging: longitudinal data analysis and machine learning.Neural regeneration research · 2023Review
- Traditional Chinese medicine promotes the control and treatment of dementia.Frontiers in pharmacology · 2022Review
- Age-Related Trajectories of Brain Structure-Function Coupling in Female Roller Derby Athletes.Brain sciences · 2021Article
- Higher spatial resolution diffusion-weighted imaging improves characterization of white matter disconnection in Alzheimer's disease.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Previous studies have demonstrated that the accumulation of amyloid-β (Aβ) pathologies has distinctive stage-specific effects on the structural and functional brain networks along the Alzheimer's disease (AD) continuum. A more comprehensive account of both types of brain network may provide a better characterization of the stage-specific effects of Aβ pathologies. A potential candidate for this joint characterization is the coupling between the structural and functional brain networks (SC-FC coupling). We therefore investigated the effect of Aβ accumulation on global SC-FC coupling in patients with mild cognitive impairment (MCI), AD, and healthy controls. Patients with MCI were dichotomized according to their level of Aβ pathology seen in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.