Evidence map›Paper›PMID 34827504›Full record

ArticleBrain sciences2021

Heart Rate Variability in Insulo-Opercular Epilepsy.

Thi Phuoc Yen Tran, Philippe Pouliot, Elie Bou Assi, Pierre Rainville, Kenneth A Myers, Manon Robert, Alain Bouthillier, Mark R Keezer, Dang Khoa Nguyen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Thi Phuoc Yen TranCHUM Research Center, University of Montreal, Montreal, QC H2X 0A9, Canada.
Philippe PouliotSafe Engineering Services and Technologies, Laval, QC H7L 6E8, Canada.
Elie Bou AssiCHUM Research Center, University of Montreal, Montreal, QC H2X 0A9, Canada.
Pierre RainvilleDepartment of Somatology, University of Montreal, Montreal, QC H3T 1J7, Canada.
Kenneth A MyersResearch Institute of the McGill University Medical Centre, Montreal, QC H3H 2R9, Canada.ORCID 0000-0001-7831-4593
Manon RobertCHUM Research Center, University of Montreal, Montreal, QC H2X 0A9, Canada.
Alain BouthillierDivision of Neurosurgery, CHUM, University of Montreal, Montreal, QC H2X 0C1, Canada.
Mark R KeezerCHUM Research Center, University of Montreal, Montreal, QC H2X 0A9, Canada.
Dang Khoa NguyenCHUM Research Center, University of Montreal, Montreal, QC H2X 0A9, Canada.
Université de Montréal · CAInstitut Universitaire de Gériatrie de Montréal · CAMontreal Children's Hospital · CASafe Engineering Services & Technologies (Canada) · CA

Funding

Canada Research Chairs DKNCIHR 390044 and 148563
6 · The paper itself

Abstract

backgroundWe aimed to evaluate heart rate variability (HRV) changes in insulo-opercular epilepsy (IOE) and after insulo-opercular surgery.

methodsWe analyzed 5-min resting HRV of IOE patients before and after surgery. Patients' SUDEP-7 risk inventory scores were also calculated. Results were compared with age- and sex-matched patients with temporal lobe epilepsy (TLE) and healthy individuals.

resultsThere were no differences in HRV measurements between IOE, TLE, and healthy control groups (and within each IOE group and TLE group) in preoperative and postoperative periods. In IOE patients, the SUDEP-7 score was positively correlated with pNN50 (percentage of successive RR intervals that differ by more than 50 ms) (

conclusionsOur results suggest that in IOE, HRV may be either decreased in parasympathetic tone or increased globally in both sympathetic and parasympathetic tones. We found no evidence that insulo-opercular surgeries lead to major autonomic dysfunction when a good seizure outcome is reached. The increase in parasympathetic tone observed preoperatively may be of clinical concern, as it was positively correlated with the SUDEP-7 score.

Indexed as

cardiac autonomic dysfunctionheart rate variabilityinsulo-opercular epilepsy

Identifiers

PMID34827504
PMCPMC8615554
OpenAlexW3214598230

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.