ReviewBrain sciences2021
Neural Mechanisms of Prism Adaptation in Healthy Adults and Individuals with Spatial Neglect after Unilateral Stroke: A Review of fMRI Studies.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Noninvasive neuromodulation for unilateral neglect after stroke: a systematic review and network meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- Effects of prism adaptation combined with electrical stimulation on cortical excitability of upper and lower limb muscles.Behavioural brain research · 2026Trial
- Short-Term Effect of Prismatic Lenses in Head Positioning and Kinematics in Patients with Postural Deficiency Syndrome.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Preliminary Evidence of Biological and Cognitive Efficacy of Prismatic Adaptation Combined with Cognitive Training on Patients with Mild Cognitive Impairment.Biomedicines · 2025Article
- Increasing affective distance - leftward prism adaptation amplifies alexithymia in healthy females.Frontiers in psychology · 2025Article
- Does prism adaptation treatment reduce spatial neglect and improve function?Frontiers in rehabilitation sciences · 2025Review
- Editorial: Advances in Understanding and Rehabilitating Unilateral Spatial Neglect.Brain sciences · 2023Article
- Prism Adaptation Treatment for Right-Sided and Left-Sided Spatial Neglect: A Retrospective Case-Matched Study.Archives of rehabilitation research and clinical translation · 2023Article
- Quantification and Rehabilitation of Unilateral Spatial Neglect in Immersive Virtual Reality: A Validation Study in Healthy Subjects.Sensors (Basel, Switzerland) · 2023Article
- Aftereffects to Prism Exposure without Adaptation: A Single Case Study.Brain sciences · 2022Article
- Choosing Sides: Impact of Prismatic Adaptation on the Lateralization of the Attentional System.Frontiers in psychology · 2022Review
- Recent advances in treatment of spatial neglect: networks and neuropsychology.Expert review of neurotherapeuticsReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Functional disability due to spatial neglect hinders recovery in up to 30% of stroke survivors. Prism adaptation treatment (PAT) may alleviate the disabling consequences of spatial neglect, but we do not yet know why some individuals show much better outcomes following PAT than others. The goal of this scoping review and meta-analysis was to investigate the neural mechanisms underlying prism adaptation (PA). We conducted both quantitative and qualitative analyses across fMRI studies investigating brain activity before, during, and after PA, in healthy individuals and patients with right or left brain damage (RBD or LBD) due to stroke. In healthy adults, PA was linked with activity in posterior parietal and cerebellar clusters, reduced bilateral parieto-frontal connectivity, and increased fronto-limbic and sensorimotor network connectivity. In contrast, RBD individuals with spatial neglect relied on different circuits, including an activity cluster in the intact left occipital cortex. This finding is consistent with a shift in hemispheric dominance in spatial processing to the left hemisphere. However, more studies are needed to clarify the contribution of lesion location and load on the circuits involved in PA after unilateral brain damage. Future studies are also needed to clarify the relationship of decreasing resting state functional connectivity (rsFC) to visuomotor function.
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Registered trials
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