Evidence map›Paper›PMID 34827455›Full record

ArticleBrain sciences2021

Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome.

Catalina Giurgi-Oncu, Cristina Tudoran, Gheorghe Nicusor Pop, Cristina Bredicean, Silvius Alexandru Pescariu, Ana Giurgiuca, Mariana Tudoran

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Post COVID-19 infection and quality of life of healthcare workers at Sahloul University Hospital of Sousse in Tunisia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  6. Review
  7. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients.International journal of environmental research and public health · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Risk factors for post-COVID cognitive dysfunctions: the impact of psychosocial vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  17. Article
  18. Neuropsychiatric aspects of long COVID: A comprehensive review.Psychiatry and clinical neurosciences · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Catalina Giurgi-OncuDepartment VIII Neurosciences, Discipline of Psychiatry, "Victor Babes" University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0001-8962-0000
Cristina Tudoran"Pius Brinzeu" County Emergency Hospital, 300723 Timisoara, Romania.ORCID 0000-0002-7351-741X
Gheorghe Nicusor PopDepartment VI, Discipline of Cardiology, "Victor Babes" University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-9947-8316
Cristina BrediceanDepartment VIII Neurosciences, Discipline of Psychiatry, "Victor Babes" University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, Romania.
Silvius Alexandru PescariuDepartment VI, Discipline of Cardiology, "Victor Babes" University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-1697-311X
Ana GiurgiucaDepartment of Clinical Neuroscience, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mariana Tudoran"Pius Brinzeu" County Emergency Hospital, 300723 Timisoara, Romania.
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · ROCarol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Post-acute COVID-19 syndrome, characterized by persisting symptoms up to 12 weeks after the acute illness, impairs numerous people's physical and mental health. (2) Methods: 64 inpatients and 79 outpatients, aged under 55 years, with post-acute COVID-19, were evaluated by a transthoracic echocardiography (TTE), mental health examination, Quality of Life (QoL) questionnaire, post-COVID-19 functional status scale (PCFS) and Hospital Anxiety and Depression Scale (HADS). (3) Results: all inpatients had mild/moderate pulmonary injury during acute COVID-19, in contrast to 37.97% of outpatients. Inpatients who reported an average of 5 persisting symptoms, had, predominantly, level 3 PCFS and a median QoL of 62, compared to outpatients, who reported an average of 3 symptoms, level 1 PCFS and a median QoL score of 70. Increased pulmonary artery pressure was detected in 28.11% of inpatients, compared to 17.72% of outpatients, while diastolic dysfunction was diagnosed in 28.12% of inpatients, in comparison with 20.25% of outpatients (

Indexed as

anxietycardiovascular complicationsdepressionmental illnesspost-acute COVID-19quality of life

Identifiers

PMID34827455
PMCPMC8615893
OpenAlexW3209310772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.