Evidence map›Paper›PMID 34827449›Full record

ArticleBrain sciences2021

DiODe v2: Unambiguous and Fully-Automated Detection of Directional DBS Lead Orientation.

Till A Dembek, Alexandra Hellerbach, Hannah Jergas, Markus Eichner, Jochen Wirths, Haidar Salimi Dafsari, Michael T Barbe, Stefan Hunsche, Veerle Visser-Vandewalle, Harald Treuer

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Till A DembekDepartment of Neurology, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.ORCID 0000-0001-7023-146X
Alexandra HellerbachDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Hannah JergasDepartment of Neurology, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Markus EichnerDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Jochen WirthsDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Haidar Salimi DafsariDepartment of Neurology, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.ORCID 0000-0001-8849-4233
Michael T BarbeDepartment of Neurology, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Stefan HunscheDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Veerle Visser-VandewalleDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.
Harald TreuerDepartment of Stereotactic and Functional Neurosurgery, Faculty of Medicine, University of Cologne, D-50937 Cologne, Germany.

Funding

Deutsche Forschungsgemeinschaft FI 773/15-1
6 · The paper itself

Abstract

Directional deep brain stimulation (DBS) leads are now widely used, but the orientation of directional leads needs to be taken into account when relating DBS to neuroanatomy. Methods that can reliably and unambiguously determine the orientation of directional DBS leads are needed. In this study, we provide an enhanced algorithm that determines the orientation of directional DBS leads from postoperative CT scans. To resolve the ambiguity of symmetric CT artifacts, which in the past, limited the orientation detection to two possible solutions, we retrospectively evaluated four different methods in 150 Cartesia™ directional leads, for which the true solution was known from additional X-ray images. The method based on shifts of the center of mass (COM) of the directional marker compared to its expected geometric center correctly resolved the ambiguity in 100% of cases. In conclusion, the DiODe v2 algorithm provides an open-source, fully automated solution for determining the orientation of directional DBS leads.

Indexed as

deep brain stimulation (DBS)directional electrodesdirectional stimulation

Identifiers

PMID34827449
PMCPMC8615850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.