Evidence map›Paper›PMID 34827426›Full record

ArticleBrain sciences2021

Striatal Dopamine Transporter Availability Is Not Associated with Food Craving in Lean and Obese Humans; a Molecular Imaging Study.

Jamie van Son, Katy A van Galen, Anne Marijn Bruijn, Karin E Koopman, Ruth I Versteeg, Susanne E la Fleur, Mireille J Serlie, Jan Booij

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jamie van SonDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-9876-2876
Katy A van GalenDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Anne Marijn BruijnDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Karin E KoopmanDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Ruth I VersteegDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Susanne E la FleurDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Mireille J SerlieDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Jan BooijDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NL

Funding

Netherlands Organisation for Health Research and Development 91112002
6 · The paper itself

Abstract

Brain dopamine signaling is essential for the motivation to eat, and obesity is associated with altered dopaminergic signaling and increased food craving. We used molecular neuroimaging to explore whether striatal dopamine transporter (DAT) availability is associated with craving as measured with the General Food Craving Questionnaire-Trait (G-FCQ-T). We here show that humans with obesity (

Indexed as

dopamine transporterfood cravingobesitySPECT

Identifiers

PMID34827426
PMCPMC8615750
OpenAlexW3211132561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.