Evidence map›Paper›PMID 34827320›Full record

ArticleAntibiotics (Basel, Switzerland)2021

A Metagenomic Nanopore Sequence Analysis Combined with Conventional Screening and Spectroscopic Methods for Deciphering the Antimicrobial Metabolites Produced by

Mohamed A Eltokhy, Bishoy T Saad, Wafaa N Eltayeb, Mona R El-Ansary, Khaled M Aboshanab, Mohamed S E Ashour

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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  6. Biologically active metabolites ofFuture science OA · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mohamed A EltokhyDepartment of Microbiology, Faculty of Pharmacy, Misr International University (MIU), Cairo 19648, Egypt.ORCID 0000-0002-5229-6291
Bishoy T SaadDepartment of Bioinformatics, HITS Solutions Co., Cairo 11765, Egypt.ORCID 0000-0003-0650-0519
Wafaa N EltayebDepartment of Microbiology, Faculty of Pharmacy, Misr International University (MIU), Cairo 19648, Egypt.ORCID 0000-0002-5309-1917
Mona R El-AnsaryDepartment of Biochemistry, Modern University for Technology and Information (MTI), Cairo 12055, Egypt.
Khaled M AboshanabDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St., Cairo 11566, Egypt.ORCID 0000-0002-7608-850X
Mohamed S E AshourDepartment of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
Misr International University · EGAin Shams University · EGAl-Azhar University · EGModern University for Information and Technology · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous development of multidrug resistance pathogens with limited therapeutic options has become a great problem globally that impose sever health hazards. Accordingly, searching for of new antimicrobials became an urgent demand and great challenge. Soil significantly have been associated with several species that are antibiotic producers. In this study, combination of conventional screening methods with Liquid chromatography- Mass spectroscopy (LC/MS) and metagenomic nanopore sequence analysis have been conducted for the deciphering the active metabolites produced by soil isolate(s). Preliminary soil screening resulted in a Gram-negative isolate identified via 16S ribosomal RNA as

Indexed as

Alcaligenes faecalisbacillibactinburkholderic acidectoineLC/MSmetagenomicsquinolobactin

Identifiers

PMID34827320
PMCPMC8614704
OpenAlexW3211795891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.