Evidence map›Paper›PMID 34827318›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Matrix-Bound Zolzoledronate Enhances the Biofilm Colonization of Hydroxyapatite: Effects on Osteonecrosis.

Ranya Elsayed, Ahmed El-Awady, Christopher Cutler, Zoya Kurago, Mahmoud Elashiry, Christina Sun, Ryan Bloomquist, Mohamed M Meghil, Mohammed E Elsalanty

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ranya ElsayedDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Ahmed El-AwadyDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Christopher CutlerDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Zoya KuragoDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Mahmoud ElashiryDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Christina SunDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Ryan BloomquistDental College of Georgia, Augusta University, Augusta, GA 30912, USA.
Mohamed M MeghilDental College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0003-2344-3579
Mohammed E ElsalantyCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Augusta University · USWestern University of Health Sciences · US

Funding

The role of zoledronate localization in the induction of osteonecrosisR15DE025134 · NIDCR · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI ELSALANTY, MOHAMMED ELSAYED HASSAN · 2015 to 2018
$889k
Carlos and Marguerite Mason Trust 001National Institute of Health S10OD025177NIDCR NIH HHS 2R15DE025134-02NIDCR NIH HHS R01DE02946801
6 · The paper itself

Abstract

(1) Background: The aim of this study was to test whether matrix-bound zoledronate (zol) molecules enhanced the oral biofilm colonization of a mineralized matrix, rendering the alveolar bone more susceptible to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures. (2) Methods: We tested the effect of matrix-bound zol on the growth and attachment of

Indexed as

anti-resorptivebiofilmbisphosphonatesMRONJoral bacteriaosteonecrosisosteoporosiszoledronates

Identifiers

PMID34827318
PMCPMC8615173
OpenAlexW3212762579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.