ArticleAntibiotics (Basel, Switzerland)2021
Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016-2018.
Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Implementation of infection prevention and control strategies in Italian intensive care units: results from the SPIN-UTI network.Antimicrobial resistance and infection control · 2025Article
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- Association between quality of governance, antibiotic consumption, and antimicrobial resistance: an analysis of Italian regions.Antimicrobial resistance and infection control · 2023Article
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- Socioeconomic and Governance Factors Disentangle the Relationship between Temperature and Antimicrobial Resistance: A 10-Year Ecological Analysis of European Countries.Antibiotics (Basel, Switzerland) · 2023Article
- How Antimicrobial Resistance Is Linked to Climate Change: An Overview of Two Intertwined Global Challenges.International journal of environmental research and public health · 2023Review
- Epidemiology of Healthcare-Associated Infections and Adherence to the HAI Prevention Strategies.Healthcare (Basel, Switzerland) · 2022Article
- Vaccination coverage in Italian children and antimicrobial resistance: an ecological analysis.Antimicrobial resistance and infection control · 2022Article
- The Inverse Relationship between Influenza Vaccination and Antimicrobial Resistance: An Ecological Analysis of Italian Data.Vaccines · 2022Article
- How COVID-19 Has Influenced Public Interest in Antimicrobials, Antimicrobial Resistance and Related Preventive Measures: A Google Trends Analysis of Italian Data.Antibiotics (Basel, Switzerland) · 2022Article
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7 authors.
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Abstract
An assessment of the burden of healthcare-associated infections (HAIs) in terms of disability-adjusted life years (DALYs) is useful for comparing and ranking HAIs and to support infection prevention and control strategies. We estimated the burden of healthcare-associated pneumoniae (HAP), bloodstream infection (HA BSI), urinary tract infection (HA UTI), and surgical site infection (SSI) in Sicily, Italy. We used data from 15,642 patients aged 45 years and above, identified during three repeated point prevalence surveys (PPSs) conducted from 2016 to 2018 according to the European Centre for Disease Prevention and Control protocol. The methodology of the Burden of Communicable Diseases in Europe project was employed. The selected HAIs accounted for 8424 DALYs (95% uncertainty interval (UI): 7394-9605) annually in Sicily, corresponding to 344 DALYs per 100,000 inhabitants aged 45 years and above (95% UI: 302-392). Notably, more than 60% of the burden was attributable to HAP, followed by HA BSI, SSI, and HA UTI. The latter had the lowest burden despite a relatively high incidence, whereas HA BSI generated a high burden even through a relatively low incidence. Differences between our estimates and those of European and Italian PPSs encourage the estimation of the burden of HAIs region by region.
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