Evidence map›Paper›PMID 34827224›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antimicrobial Effect of Isotretinoin Therapy on Periodontal Pathogens: A Case-Control Study.

Reham AlJasser, Razan AlAqeely, Afnan AlZahrani, Manal AlKenani, Sadeem AlQahtani, Mohammed AlSarhan, Dalal AlOtaibi, Rhodanne Lambarte

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Reham AlJasserDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.ORCID 0000-0002-5783-9697
Razan AlAqeelyDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
Afnan AlZahraniMinistry of Health, Riyadh 11176, Saudi Arabia.
Manal AlKenaniSaudi Board of Periodontics, Riyadh 11545, Saudi Arabia.
Sadeem AlQahtaniSaudi Board of Periodontics, Riyadh 11545, Saudi Arabia.
Mohammed AlSarhanDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.ORCID 0000-0003-3389-1914
Dalal AlOtaibiDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
Rhodanne LambarteMolecular and Cell Biology Laboratory, Prince Naif Bin AbdulAziz Health Research Center, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
King Saud University · SASaudi Center for Organ Transplantation · SAKing Saud bin Abdulaziz University for Health Sciences · SAMinistry of Health · SA

Funding

Dean- ship of Scientific Research at King Saud University RG-1441- 498
6 · The paper itself

Abstract

Isotretinoin (INN), a drug used to treat severe acne, has anti-inflammatory and antibacterial properties. INN may affect periodontal pathogenic bacteria, so we aimed to study the effect of INN on intraoral microbial profiles of periodontal disease and healthy periodontium. Our case-control study divided 180 subjects into six groups according to periodontal health status and INN usage as follows: healthy periodontium receiving INN (HINN;

Indexed as

isotretinoinoral microbesperiodontal pathogensperiodontal therapy

Identifiers

PMID34827224
PMCPMC8615252
OpenAlexW3205158998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.