Evidence map›Paper›PMID 34827066›Full record

ArticleBiology2021

Performance of Scoring Systems in Predicting Clinical Outcomes in Patients with Bacteremia of

Shang-Hsuan Huang, Ming-Shun Hsieh, Sung-Yuan Hu, Shih-Che Huang, Che-An Tsai, Chiann-Yi Hsu, Tzu-Chieh Lin, Yi-Chen Lee, Shu-Hui Liao

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Shang-Hsuan HuangDepartment of Emergency Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Ming-Shun HsiehDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330, Taiwan.
Sung-Yuan HuDepartment of Emergency Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Shih-Che HuangSchool of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Che-An TsaiDivision of Infectious Disease, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Chiann-Yi HsuBiostatistics Task Force, Department of Medical Research, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Tzu-Chieh LinDepartment of Emergency Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.ORCID 0000-0002-6542-2023
Yi-Chen LeeDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330, Taiwan.
Shu-Hui LiaoDepartment of Pathology and Laboratory, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330, Taiwan.
Taichung Veterans General Hospital · TWTaipei Veterans General Hospital · TWNational Chung Hsing University · TWNational Taichung University of Science and Technology · TWNational Yang Ming Chiao Tung University · TW

Funding

Taichung Veterans General Hospital TCVGH-1107202C
6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsThis was a hospital-based retrospective study on patients with bacteremia of LM. Data were collected from the electronic clinical database of Taichung Veterans General Hospital between January 2012 and December 2020. Bacteremia of LM was confirmed by at least one blood culture. Demographics, clinical characteristics, and laboratory data were collected for analysis. A variety of clinical scoring systems were used to predict the clinical outcome.

resultsA total of 39 patients had confirmed bacteremia of LM. Among them, 1 neonatal patient was excluded. The remaining 38 patients were studied. They included 16 males (42.1%) and 22 females (57.9%), with a mean age of 59.9 ± 19.6 years. Their hospital stay averaged 23.3 ± 20.9 days. The in-hospital mortality rate was 36.8%. Mortality in Emergency Department Sepsis (MEDS) Score was 6.6 ± 4.0 for survivors and 12.4 ± 4.4 for non-survivors (P < 0.001). The National Early Warning Score (NEWS) was 3.9 ± 2.8 for survivors and 7.8 ± 3.1 for non-survivors (P = 0.001). Regarding the prediction of mortality risk, the AUC of ROC was 0.829 for MEDS and 0.815 for NEWS.

conclusionsMEDS and NEWS were both good predictors of the clinical outcome in LM bacteremic patients. In those with higher scores of MEDS (≥10) and NEWS (≥8), we recommended an early goal-directed therapy and appropriate antibiotic treatment as early as possible to reduce mortality. Further large-scale studies are required to gain a deeper understanding of this disease and to ensure patient safety.

Indexed as

area under the curve (AUC)bacteremiaListeria monocytogenes (LM)mortality in emergency department sepsis (MEDS) scorenational early warning score (NEWS)receiver operating characteristic curve (ROC)scoring systems

Identifiers

PMID34827066
PMCPMC8615254
OpenAlexW3209960832

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.