Evidence map›Paper›PMID 34826996›Full record

ArticleIndian journal of ophthalmology2021

Outcomes of combined treatments in patients with retinal arterial macroaneurysm.

Chenghu Wang, Guofan Cao, Xiangzhong Xu, Jian Wang, Shu Zhang

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Anti-VEGF therapy for symptomatic exudative retinal arterial macroaneurysms: functional and anatomic outcomes with OCTA findings.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chenghu WangAffiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Guofan CaoAffiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Xiangzhong XuAffiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Jian WangSchool of Communication Science and Disorders, Dalhousie University, Halifax, Canada.
Shu ZhangAffiliated Eye Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNDalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the outcome of the combined approach between intravitreal ranibizumab (IVR) and focal laser photocoagulation (FLP) in the treatment of symptomatic retinal arterial macroaneurysm (RAM).

methodsA total of 10 patients were included in this clinical case series report. They were diagnosed with symptomatic RAM (one eye in each) and assessed by a comprehensive ophthalmologic examination, including fluorescein angiography (FA), optical coherence tomography angiography (OCT-A), and indocyanine green angiography (ICGA). All patients were treated with an IVR followed by an FLP 2 weeks later. If necessary, a second IVR was given 1 month after the first one (or 2 weeks after the first FLP), which was followed by a second FLP treatment 2 weeks later in the needed cases. All cases were followed up for 6 months after the last treatment.

resultsBoth the retina hemorrhage and edema were resolved by the treatment. No ocular and/or systemic side effects were evident, and no recrudescence of RAM was seen within the 6 months of follow-up.

conclusionThe combined treatment of IVRs and FLPs was successful in the management of symptomatic RAM.

Indexed as

Retinal Arterial MacroaneurysmAngiogenesis InhibitorsFluorescein AngiographyHumansIntravitreal InjectionsRanibizumabTomography, Optical CoherenceVisual AcuityAngiogenesis InhibitorsRanibizumabAtherosclerosisfocal laser photocoagulationhypertensionintravitreal ranibizumab injectionretinal arterial macroaneurysm

Identifiers

PMID34826996
PMCPMC8837312
OpenAlexW3217589929

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.