Evidence map›Paper›PMID 34826995›Full record

Trial reportIndian journal of ophthalmology2021

Effect of short-term meditation training in central serous chorioretinopathy.

Grisilda Nongrem, Abhidnya Surve, Pradeep Venkatesh, Rajesh Sagar, Raj K Yadav, Rohan Chawla, Rajpal Vohra, Atul Kumar

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Interventions for central serous chorioretinopathy: a network meta-analysis.The Cochrane database of systematic reviews · 2025
    Pooled it
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  3. Comparing treatment outcomes in randomized controlled trials of central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Grisilda NongremVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Abhidnya SurveVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Pradeep VenkateshVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Rajesh SagarDepartment of Psychiatry; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Raj K YadavDepartment of Physiolology; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Rohan ChawlaVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Rajpal VohraVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Atul KumarVitreo-Retina, Uvea and ROP Services; Dr. Rajendra Prasad Center for Ophthalmic Sciences; All India Institute of Medical Sciences (AIIMS), New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStress and Type A personality are established risk factors for the development of central serous chorioretinopathy (CSC). Meditation is known to have a positive effect on reducing stress levels. This study aimed to assess the effect of short-term meditation training in patients of CSC.

methodsA pilot study was conducted where 40 patients diagnosed with acute and non-resolving CSC were randomly assigned to either of two groups - meditation training and routine care (without meditation). The primary outcome measure was time to resolution of CSC based on optical coherence tomography and fluorescein angiography. Secondary outcome measures were changes in anxiety score (State-Trait Anxiety Inventory [STAI] scores) and blood pressure. The patients were followed up for a minimum period of 4 months.

resultsTwenty cases were included in each group. The demographic pattern, baseline swept-source optical coherence tomography parameters, and STAI scores were similar in both groups. The time to disease resolution was 9.4 ± 4.22 weeks in the meditation group and 19.5 ± 2.79 weeks in the nonmeditation group (P < 0.001). At 4 months, CSC had failed to resolve in 60% of patients with routine care compared with 8% in cases following short-term meditation training. STAI scores showed a reduction in stress levels in the meditation group. Furthermore, statistically significant improvement in systolic and diastolic blood pressures was also observed following meditation training.

conclusionShort-term meditation training may be a useful approach in the management of patients with CSC as it tends to reduce stress and prehypertension, and promotes earlier resolution of the condition. However, patient's motivation to complete and pursue the meditation training is a significant barrier.

Indexed as

Central Serous ChorioretinopathyMeditationFluorescein AngiographyHumansPilot ProjectsRetrospective StudiesTomography, Optical CoherenceVisual AcuityCentral serous chorioretinopathymeditationoptical coherence tomographystress

Identifiers

PMID34826995
PMCPMC8837379
OpenAlexW3215702594

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.