ReviewIndian journal of ophthalmology2021
After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines.
Review in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review.International ophthalmology · 2024Pooled it
- Article
- The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Considerations of COVID-19 in Ophthalmology.Microorganisms · 2023Review
- Dacryoadenitis post COVID-19 infection and immunization.Indian journal of ophthalmology · 2023Article
- Covid-19 and its relation to the human eye: transmission, infection, and ocular manifestations.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
- Retinal vascular occlusion following SARS-CoV-2 vaccination: A VAERS database analysis.Ophthalmology science · 2023Article
- Evaluation of the Effect of İnfection and İmmunity on the Tear Film by Scheimpflug-Placido Disc Topography- A Case Control Study.Photodiagnosis and photodynamic therapy · 2023Article
- COVID-19 vaccination and corneal allograft rejection- a review.Frontiers in cellular and infection microbiology · 2023Review
- Unilateral Episcleritis Following COVID-19 Booster Vaccination of a Crohn's Disease Patient: A Case Report and Review of the Literature.International medical case reports journal · 2023Article
- Bilateral choroidal effusion following vaccination against SARS-CoV-2 virus.Indian journal of ophthalmology · 2022Article
- Bilateral retinal vein occlusion after two doses of SARS-CoV-2 adenovirus vector-based vaccine.Journal francais d'ophtalmologie · 2022Article
- Comments on: After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines.Indian journal of ophthalmology · 2022Article
- Bilateral multifocal choroiditis with disc edema in a 15-year-old girl following COVID-19 vaccination.Indian journal of ophthalmology · 2022Article
- A Review of Corneal Transplantation: An Insight on the Overall Global Post-COVID-19 Impact.Cureus · 2022Review
- Retinal Vascular Occlusion after COVID-19 Vaccination: More Coincidence than Causal Relationship? Data from a Retrospective Multicentre Study.Journal of clinical medicine · 2022Article
- Characteristics and Clinical Ocular Manifestations in Patients with Acute Corneal Graft Rejection after Receiving the COVID-19 Vaccine: A Systematic Review.Journal of clinical medicine · 2022Review
- Article
- Review
- Analysis of macular structure in age-related cataract patients with different antibody levels of severe acute respiratory syndrome coronavirus-2 vaccine.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several COVID-19 vaccines have been developed and approved for use around the world from December 2020, to combat the pandemic caused by the novel SARS-CoV-2 virus. Several ophthalmic manifestations of the COVID-19 vaccines have been reported by ophthalmologists. This review was undertaken to recognize, encourage active reporting and determine the pathogenesis and time of appearance for better awareness and understanding of the ophthalmic manifestations of COVID-19 vaccines. A literature search was performed for publications on the ophthalmic manifestations of COVID-19 vaccines between January 1, 2021 and November 7, 2021. 23 case reports, 17 letters to editors, 3 ophthalmic images, 4 brief communications, 4 retrospective cohort studies and 2 case control studies were included. Posterior segment, including the uvea, choroid and retinal vasculature, was most commonly affected and the reported clinical features developed at a median of four days from the time of vaccination. The possible mechanisms include molecular mimicry of the vaccine components with host ocular tissues, antigen-specific cell and antibody-mediated hypersensitivity reactions to viral antigens and adjuvants present in the vaccines. The causal relationship of the ocular signs and symptoms and COVID-19 vaccines has not been established and requires long-term and large multicentre data. Most of the reported manifestations are mild, transient and adequately treated when diagnosed and managed early. The benefits of COVID-19 vaccination outweighs the reported rare adverse events and should not be a deterrent to vaccination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.