Evidence map›Paper›PMID 34826375›Full record

ArticleThe Journal of international medical research2021

Antimicrobial prescribing and outcomes of community-acquired pneumonia in Australian hospitalized patients: a cross-sectional study.

Lawless Robert, Vickers Mark, Alawami Moayed, Appasamy Nivashen, Rajasingam Vinod, Paviour Sophie, El Washahy Mohamed, Chew Rusheng

Abstract read
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Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lawless RobertFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.
Vickers MarkFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.ORCID https://orcid.org/0000-0002-2831-404X
Alawami MoayedFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.
Appasamy NivashenFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.
Rajasingam VinodFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.
Paviour SophieSchool of Pharmacy, The University of Queensland, Queensland, Australia.
El Washahy MohamedFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.
Chew RushengFaculty of Medicine, 1974The University of Queensland, The University of Queensland, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to assess prescribing practices, compliance with guidelines, and outcomes for patients who were admitted to the authors' institution with community-acquired pneumonia (CAP).

methodsWe performed a single-center retrospective cross-sectional study of adults with CAP presenting during the 2019 influenza season. CAP severity was assessed using the CURB-65 risk score. The effect of CURB-65 risk score use on the rate of appropriate antimicrobial prescribing was assessed using the chi-square test and reported as odds ratio (OR). Fisher's exact test was used to assess the relationship between prescribing appropriateness and patient outcomes.

resultsPatients with low-risk CAP were most likely to be inappropriately prescribed antimicrobials (OR: 4.77; 95% confidence interval: 2.44-10.47). In low-risk CAP, the most common prescribing error was overuse of ceftriaxone. In high-risk CAP, the most common errors were ceftriaxone underdosing and missed atypical coverage with azithromycin. Overall, 80% of patients were considered to have been inappropriately prescribed antimicrobials. No effect on mortality was observed.

conclusionsIn this study, we found low use of CAP risk scores and low adherence to antimicrobial prescribing guidelines for CAP at the authors' institution.

Indexed as

Anti-Infective AgentsCommunity-Acquired InfectionsPneumoniaAdultAnti-Bacterial AgentsAustraliaCross-Sectional StudiesHumansRetrospective StudiesAnti-Bacterial AgentsAnti-Infective Agentsanti-bacterial agentantimicrobial stewardshipemergency medicinePneumoniapractice guidelinesrespiratory medicine

Identifiers

PMID34826375
PMCPMC8647258

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.