Evidence map›Paper›PMID 34826233›Full record

ArticleScience advances2021

Whole-animal multiplexed single-cell RNA-seq reveals transcriptional shifts across

Tara Chari, Brandon Weissbourd, Jase Gehring, Anna Ferraioli, Lucas Leclère, Makenna Herl, Fan Gao, Sandra Chevalier, Richard R Copley, Evelyn Houliston and 2 more

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Decoding cnidarian cell type gene regulation.Nature ecology & evolution · 2026
    Article
  10. Review
  11. Article
  12. Marine Model Organisms for Mechanobiology Studies.Results and problems in cell differentiation · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. A plea for academic truth.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025
    Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tara ChariDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-6953-4313
Brandon WeissbourdDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-5422-3873
Jase GehringDepartment of Genome Sciences, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-3894-9495
Anna FerraioliSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), 06230, France.ORCID 0000-0003-1817-6891
Lucas LeclèreSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), 06230, France.ORCID 0000-0002-7440-0467
Makenna HerlUniversity of New Hampshire School of Law, Concord, NH 03301, USA.ORCID 0000-0001-8518-5179
Fan GaoCaltech Bioinformatics Resource Center, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-6832-3402
Sandra ChevalierSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), 06230, France.ORCID 0000-0002-2717-6925
Richard R CopleySorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), 06230, France.ORCID 0000-0001-7846-4954
Evelyn HoulistonSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), 06230, France.ORCID 0000-0001-9264-2585
David J AndersonDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-6175-3872
Lior PachterDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-9164-6231

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7M
Region-Specific, Inducible Axonal Tract-Tracing in the BrainR01MH070053 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI David J Anderson · 2004 to 2026
$9.7M
SUGAR-seq: A New Technology for Single-Cell Glycan and Gene Expression Profiling in ADRF1AG062324 · NIA · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HSIEH-WILSON, LINDA C · 2018 to 2018
$3.3M
Multimodal, integrated analysis of neural activity and naturalistic social behavior in freely moving miceR01MH123612 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSON, DAVID J, PERONA, PIETRO · 2020 to 2024
$2.1M
A new animal model to examine nervous system function, development, and regenerationK99NS119749 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WEISSBOURD, BRANDON · 2021 to 2022
$251k
NIA NIH HHS RF1 AG062324NIMH NIH HHS R01 MH070053NIMH NIH HHS R01 MH123612NIMH NIH HHS U19 MH114830NINDS NIH HHS K99 NS119749
6 · The paper itself

Abstract

We present an organism-wide, transcriptomic cell atlas of the hydrozoan medusa

Identifiers

PMID34826233
PMCPMC8626072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.