Evidence map›Paper›PMID 34825984›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Risk factors for surgical site infection in head and neck cancer.

Chengwen Gan, Yannan Wang, Yan Tang, Kai Wang, Bincan Sun, Mengxue Wang, Feiya Zhu

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chengwen Gan *Department of Oral and Maxillofacial Surgery, Hainan Provincial People's Hospital, Haikou, Hainan, China.
Yannan Wang *Department of Plastic Surgery, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Yan TangDepartment of Nursing, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Kai WangDepartment of Oral and Maxillofacial Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Road, Changsha, Hunan, China.
Bincan SunDepartment of Oral and Maxillofacial Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Road, Changsha, Hunan, China.
Mengxue WangDepartment of Oral and Maxillofacial Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Road, Changsha, Hunan, China.
Feiya ZhuDepartment of Oral and Maxillofacial Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Road, Changsha, Hunan, China. physics4@csu.edu.cn.ORCID http://orcid.org/0000-0003-0268-6336
Central South University · CNGuangdong General Hospital · CNHainan General Hospital · CNSecond Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical site infection (SSI) frequently occurs in patients with head and neck cancer (HNC) after tumor resection and can lead to death in severe cases. Moreover, there is no definitive conclusion about the risk factors of SSI. Therefore, it is of great clinical significance to study the factors affecting the SSI.

methodsThe HNC patients included in this study were all from the Department of Oral and Maxillofacial Surgery of the Second Xiangya Hospital of Central South University (CSU), and these patients received surgical treatment in the department from January 2018 to December 2019. The cross tabulation with chi-squared testing and multivariate regression analysis were applied to determine the risk factors of SSI. To identify the key risk factors of SSI, the caret package was used to construct three different machine learning models to investigate important features involving 26 SSI-related risk factors.

resultsParticipants were 632 HNC patients who underwent surgery in our department from January 2018 to December 2019. During the postoperative period, 82 patients suffered from SSI, and surgical site infection rate (SSIR) was about 12.97%. Multivariate logistic regression analysis shows that diabetes mellitus, primary tumor site (floor of mouth), preoperative radiotherapy, flap failure, and neck dissection (bilateral) are risk factors for SSI of HNC. Machine learning indicated that diabetes mellitus, primary tumor site (floor of mouth), and flap failure were consistently ranked the top three in the 26 SSI-related risk factors.

conclusionDiabetes mellitus, primary tumor site (floor of mouth), flap failure, preoperative radiotherapy, and neck dissection (bilateral) are risk factors for SSI of HNC.

Indexed as

Head and Neck NeoplasmsSurgical Wound InfectionHumansNeck DissectionRetrospective StudiesRisk FactorsDiabetes mellitusFlap failureHead and neck cancerPreoperative radiotherapySurgical site infectionTumor site

Identifiers

PMID34825984
OpenAlexW3171893865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.