SynthesisInternational journal of colorectal disease2022
Prevalence of 'pouch failure' of the ileoanal pouch in ulcerative colitis: a systematic review and meta-analysis.
Synthesis in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Perineal salvage surgery for prolapse of ileal pouch anal anastomosis: Systematic review and meta-analysis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- Review
- Article
- Biological therapies for inflammatory pouch disorders: insights and outcomes from the RESERVO study of GETECCU.Therapeutic advances in gastroenterology · 2026Article
- Fecal microbiota transplantation from a healthy pouch donor for chronic pouchitis: a proof-of-concept study.Gut microbes · 2025Article
- Sacral neuromodulation improves functional outcome and quality of life in patients with pouch dysfunction after pan proctocolectomy for ulcerative colitis.Techniques in coloproctology · 2025Article
- Crohn's-like Ileal Pouch Illness and Ileal Pouch Salvage Strategies.Clinics in colon and rectal surgery · 2025Review
- Diverting ileostomy for treatment of ileoanal pouch dysfunction: a technical note.International journal of colorectal disease · 2024Article
- Open vs. laparoscopic vs. robotic pouch excision: unveiling the best approach for optimal outcomes.Techniques in coloproctology · 2024Article
- 2-Stage and 3-stage restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis show comparable short- and long-term outcomes.Scientific reports · 2024Article
- Robotic-assisted reoperative ileal pouch-anal anastomosis: robotic pouch excision and pouch revision.Techniques in coloproctology · 2024Article
- Current Status and Surgical Technique for Restorative Proctocolectomy with Ileal Pouch Anal AnastomosisBalkan medical journal · 2023Review
- Very Early Pouchitis Is Associated with an Increased Likelihood of Chronic Inflammatory Conditions of the Pouch.Digestive diseases and sciences · 2023Article
- Predictors of pouch failure: A tertiary care inflammatory bowel disease centre experience.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2023Article
- Pelvic Pouch Failure: Treatment Options.Clinics in colon and rectal surgery · 2022Review
- Managing ulcerative colitis after surgery.Frontiers in medicine · 2022Review
- Current Perspectives on Indications for Ileal Pouch-Anal Anastomosis in Older Patients.Clinical and experimental gastroenterology · 2022Review
- Endoscopic management of ileal pouch-anal anastomosis strictures: meta-analysis and systematic literature review.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe ileoanal pouch (IPAA) provides patients with ulcerative colitis (UC) that have not responded to medical therapy an option to retain bowel continuity and defecate without the need for a long-term stoma. Despite good functional outcomes, some pouches fail, requiring permanent diversion, pouchectomy, or a redo pouch. The incidence of pouch failure ranges between 2 and 15% in the literature. We conducted a systematic review and meta-analysis aiming to define the prevalence of pouch failure in patients with UC who have undergone IPAA using population-based studies.
methodsWe searched Embase, Embase classic and PubMed from 1978 to 31st of May 2021 to identify cross-sectional studies that reported the prevalence of pouch failure in adults (≥ 18 years of age) who underwent IPAA for UC.
resultsTwenty-six studies comprising 23,389 patients were analysed. With < 5 years of follow-up, the prevalence of pouch failure was 5% (95%CI 3-10%). With ≥ 5 but < 10 years of follow-up, the prevalence was 5% (95%CI 4-7%). This increased to 9% (95%CI 7-16%) with ≥ 10 years of follow-up. The overall prevalence of pouch failure was 6% (95%CI 5-8%).
conclusionsThe overall prevalence of pouch failure in patients over the age of 18 who have undergone restorative proctocolectomy in UC is 6%. These data are important for counselling patients considering this operation. Importantly, for those patients with UC being considered for a pouch, their disease course has often resulted in both physical and psychological morbidity and hence providing accurate expectations for these patients is vital.
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