ArticleWorld journal of urology2022
External validation of the Palacios' equation: a simple and accurate tool to estimate the new baseline renal function after renal cancer surgery.
Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The role of warm ischemia time on functional outcomes after robotic partial nephrectomy: a radionuclide renal scan study from the clock randomized trial.World journal of urology · 2023Trial
- Proteomic analysis of plasma extracellular vesicles for predicting acute kidney injury following laparoscopic radical nephrectomy.Scientific reports · 2026Article
- CT volumetric analysis: association of renal parenchyma and GFR alteration in nephrectomy patients.Abdominal radiology (New York) · 2025Article
- Creation of a Rehabilitation Prediction Rule: a Prioritization Procedure.Canadian geriatrics journal : CGJ · 2025Article
- How to optimize the use of adjuvant pembrolizumab in renal cell carcinoma: which patients benefit the most?World journal of urology · 2022Article
- Predicting GFR after radical nephrectomy: the importance of split renal function.World journal of urology · 2022Article
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14 authors.
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Abstract
purposeTo externally validate the Palacios' equation estimating the new baseline glomerular filtration rate (NB-GFR) after partial or radical-nephrectomy (PN, RN) for Renal cancer carcinoma (RCC). MATERIALS AND
methodsOur research group recently published two studies that investigated the association between renal function and cancer-specific survival in RCC. The first one included 3457 patients undergone RN or PN for a cT1-2 RCC coming from five high-volume centers; the second one considered 1767 patients undergone RN or PN for a cT1-4 RCC in a single high-volume center. From such datasets, available complete patients' data were used to calculate the predicted NB-GFR through the Palacios' equation: predicted NB-GFR = 35.03 + 0.65 ∙ preoperative GFR - 18.19 ∙ (if radical nephrectomy) - 0.25 ∙ age + 2.83 ∙ (if tumor size > 7 cm) - 2.09 ∙ (if diabetes). The observed NB-GFR was calculated by the CKD-EPI equation on serum creatinine at 3-12 months after surgery. Concordance between observed and predicted NB-GFR was evaluated by Lin's concordance correlation coefficient and Bland-Altman analysis.
results2419 patients were included (1210, cohort #1; 1219, cohort #2). The median observed NB-GFR value in cohorts #1 and #2 was 73.0 ml/min/1.73 m
conclusionsWe confirm the predictive performances of Palacios' equation, supporting its utilization in clinical practice.
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