Evidence map›Paper›PMID 34825929›Full record

ArticleIntensive care medicine2022

Mechanisms of oxygenation responses to proning and recruitment in COVID-19 pneumonia.

Sandra Rossi, Maria Michela Palumbo, Nicola Sverzellati, Mattia Busana, Laura Malchiodi, Paolo Bresciani, Patrizia Ceccarelli, Emanuele Sani, Federica Romitti, Matteo Bonifazi and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  13. Prone positioning.Intensive care medicine · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 4 countries.

Sandra Rossi *Department of Anesthesiology and Intensive Care Medicine, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Maria Michela Palumbo *Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Nicola SverzellatiRadiology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Mattia BusanaDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Laura MalchiodiDepartment of Anesthesiology and Intensive Care Medicine, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Paolo BrescianiRadiology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Patrizia CeccarelliDepartment of Anesthesiology and Intensive Care Medicine, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Emanuele SaniDepartment of Anesthesiology and Intensive Care Medicine, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Federica RomittiDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Matteo BonifaziDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Simone GattarelloDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Irene SteinbergDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Paola PalermoDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Stefano LazzariDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Francesca CollinoDepartment of Anesthesia, Intensive Care and Emergency - 'Città della Salute e della Scienza' Hospital, Turin, Italy.
Massimo CressoniDepartment of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Peter HerrmannDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Leif SaagerDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Konrad MeissnerDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Michael QuintelDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.
Luigi CamporotaDepartment of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, Health Centre for Human and Applied Physiological Sciences, London, UK.
John J MariniDepartment of Pulmonary and Critical Care Medicine, University of Minnesota and Regions Hospital, St. Paul Minnesota, USA.
Luciano GattinoniDepartment of Anesthesiology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany. gattinoniluciano@gmail.com.ORCID http://orcid.org/0000-0001-5380-2494
Universitätsmedizin Göttingen · DEOspedale di Parma · ITVita-Salute San Raffaele University · ITUniversity of Parma · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITGuy's and St Thomas' NHS Foundation Trust · GBIRCCS Policlinico San Donato · ITRegions Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed at investigating the mechanisms underlying the oxygenation response to proning and recruitment maneuvers in coronavirus disease 2019 (COVID-19) pneumonia.

methodsTwenty-five patients with COVID-19 pneumonia, at variable times since admission (from 1 to 3 weeks), underwent computed tomography (CT) lung scans, gas-exchange and lung-mechanics measurement in supine and prone positions at 5 cmH

resultsThe average values of venous admixture and PaO

conclusionThe amount of consolidated tissue was higher in patients assessed during the third week and determined the oxygenation responses following pronation and recruitment maneuvers.

Indexed as

COVID-19Respiratory Distress SyndromeHumansLungProne PositionProspective StudiesPulmonary Gas ExchangeSARS-CoV-2ARDSCOVID-19Lung recruitmentMechanical ventilationProne position

Identifiers

PMID34825929
PMCPMC8617364
OpenAlexW3215922989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.