ArticleEmerging microbes & infections2022
Emergence, prevalence, and evolution of H5N8 avian influenza viruses in central China, 2020.
Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Meta-analysis of Newcastle disease virus prevalence among poultry in mainland China.Open veterinary journal · 2025Pooled it
- Evolving dynamics of H5Nx avian influenza in China revealed by long-term wild bird surveillance.Nature communications · 2026Article
- The role of wild birds in the global highly pathogenic avian influenza H5 panzootic, 2020-2023.npj biodiversity · 2026Review
- Epidemiology, evolution, and biological characteristics of avian influenza A (H11) viruses from wild birds.Virulence · 2025Article
- Review of avian influenza outbreaks in Nigeria 2006-2025.Open veterinary journal · 2025Review
- Evaluation of global distribution, genetic evolution, and mammalian infectivity and pathogenicity of H13 and H16 avian influenza viruses.Emerging microbes & infections · 2025Article
- Clade 2.3.4.4b highly pathogenic H5N1 influenza viruses from birds in China replicate effectively in bovine cells and pose potential public health risk.Emerging microbes & infections · 2025Article
- Long-term surveillance of avian avulavirus in wild birds in China from 2003 to 2020.Virologica Sinica · 2025Article
- Molecular surveillance confirms absence of avian influenza virus type A in Ecuadorian poultry: A retrospective reverse transcription quantitative polymerase chain reaction study from April 2023 to June 2024.Veterinary world · 2025Article
- Genetic diversity of highly pathogenic avian influenza H5N6 and H5N8 viruses in poultry markets in Guangdong, China, 2020-2022.Journal of virology · 2025Article
- H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication.PLoS pathogens · 2024Article
- Evolution and Spread of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea, 2022-2023.Emerging infectious diseases · 2024Article
- Spatiotemporal and Species-Crossing Transmission Dynamics of Subclade 2.3.4.4b H5Nx HPAIVs.Transboundary and emerging diseases · 2024Article
- Emergence of HPAI H5N6 Clade 2.3.4.4b in Wild Birds: A Case Study From South Korea, 2023.Transboundary and emerging diseases · 2024Article
- Article
- Emerging Highly Pathogenic Avian Influenza (H5N8) Virus inTransboundary and emerging diseases · 2023Article
- Global review of the H5N8 avian influenza virus subtype.Frontiers in microbiology · 2023Review
- Machine learning approach combined with causal relationship inferring unlocks the shared pathomechanism between COVID-19 and acute myocardial infarction.Frontiers in microbiology · 2023Article
- Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China.Emerging microbes & infections · 2022Article
- Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Virus Clade 2.3.4.4h in Mammals.Viruses · 2022Article
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Authors and funding
29 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly pathogenic influenza A(H5N8) viruses have caused several worldwide outbreaks in birds and are able cross the species barrier to infect humans, posing a substantial threat to public health. After the first detection of H5N8 viruses in deceased swans in Inner Mongolia, we performed early warning and active monitoring along swan migration routes in central China. We isolated and sequenced 42 avian influenza viruses, including 40 H5N8 viruses, 1 H5N2 virus, and 1 H9N2 virus, in central China. Our H5N8 viruses isolated in swan stopover sites and wintering grounds showed high nucleotide homologies in the whole genome, revealing a common evolutionary source. Phylogenetic analysis revealed that the H5 viruses of clade 2.3.4.4b prevalent in 2020 have further diverged into two sub-clades: b1 and b2. The phylogeographic analysis also showed that the viruses of sub-clade b2 most likely originated from poultry in Russia. Notably, whooper swans were found to be responsible for the introduction of sub-clade b2 viruses in central China; whooper and tundra swans play a role in viral spread in the Yellow River Basin and the Yangtze River Basin, respectively. Our findings highlight swans as an indicator species for transborder spreading and monitoring of the H5N8 virus.
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