Evidence map›Paper›PMID 34825600›Full record

ReviewIntegrative cancer therapies

Traditional Chinese Medicine Therapy for Esophageal Cancer: A Literature Review.

Luchang Cao, Xinmiao Wang, Guanghui Zhu, Shixin Li, Heping Wang, Jingyuan Wu, Taicheng Lu, Jie Li

Open access · goldAbstract readReview
In one paragraph

Review in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  7. Review
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  9. Review
  10. Article
  11. Article
  12. Multi-Components in ModifiedClinical and experimental gastroenterology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Luchang CaoGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xinmiao WangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Guanghui ZhuGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Shixin LiGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Heping WangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jingyuan WuGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Taicheng LuGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jie LiGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-3461-8816
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer (EC) is the sixth leading cause of cancer-related deaths worldwide. Western medicine has played a leading role in its treatment, but its prognosis remains unsatisfactory. Therefore, the development of effective therapies is important. Traditional Chinese medicine (TCM) has been practiced for thousands of years, and involves taking measures before diseases occur, deteriorate, and recur. Interestingly, there is growing evidence that TCM can improve the therapeutic effects in reversing precancerous lesions, inhibiting the recurrence and metastasis of EC. In this article, we review traditional Chinese herbs and formulas that have preventive and therapeutic effects on EC, summarize the application and research status of TCM in patients with EC, and discuss its shortcomings and prospects in the context of translational, evidence-based, and precision medicine.

Indexed as

Drugs, Chinese HerbalEsophageal NeoplasmsHumansMedicine, Chinese TraditionalPrecision MedicineDrugs, Chinese Herbalcomplementary and alternative medicineesophageal cancermechanismtherapytraditional Chinese medicine

Identifiers

PMID34825600
PMCPMC8649093
OpenAlexW3215769707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.