ArticleVox sanguinis2022
Prediction and impact of personalized donation intervals.
Article in Vox sanguinis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Study on Predictive Methods for Delayed Blood Donation Due to Low Hemoglobin: Evidence Based on Blood Donation Data in Hangzhou, China.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026Article
- Potential benefits of an alternative haemoglobin deferral strategy evaluated in seven countries.Vox sanguinis · 2026Article
- Donor and non-donor perspectives on receiving information from routine genomic testing of donor blood.Transfusion · 2023Article
- Prediction and impact of personalized donation intervals.Vox sanguinis · 2022Article
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Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
objectivesDeferral of blood donors due to low haemoglobin (Hb) is demotivating to donors, can be a sign for developing anaemia and incurs costs for blood establishments. The prediction of Hb deferral has been shown to be feasible in a number of studies based on demographic, Hb measurement and donation history data. The aim of this paper is to evaluate how state-of-the-art computational prediction tools can facilitate nationwide personalized donation intervals. MATERIALS AND
methodsUsing donation history data from the last 20 years in Finland, FinDonor blood donor cohort data and blood service Biobank genotyping data, we built linear and non-linear predictors of Hb deferral. Based on financial data from the Finnish Red Cross Blood Service, we then estimated the economic impacts of deploying such predictors.
resultsWe discovered that while linear predictors generally predict Hb relatively well, they have difficulties in predicting low Hb values. Overall, we found that non-linear or linear predictors with or without genetic data performed only slightly better than a simple cutoff based on previous Hb. However, if any of our deferral prediction methods are used to assign temporary prolongations of donation intervals for females, then our calculations indicate cost savings while maintaining the blood supply.
conclusionWe find that even though the prediction accuracy is not very high, the actual use of any of our predictors in blood collection is still likely to bring benefits to blood donors and blood establishments alike.
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