Evidence map›Paper›PMID 34825274›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2022

Association between the time to definitive care and trauma patient outcomes: every minute in the golden hour matters.

Shang-Lin Hsieh, Chien-Han Hsiao, Wen-Chu Chiang, Sang Do Shin, Sabariah Faizah Jamaluddin, Do Ngoc Son, Ki Jeong Hong, Sun Jen-Tang, Weide Tsai, Ding-Kuo Chien and 3 more

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Chinese expert consensus on the prehospital management of major trauma.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
    Article
  7. Observational
  8. Review
  9. Article
  10. Article
  11. Disparities in Access to Trauma Care in Canada: A Geospatial Analysis of Census Data.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  12. Polytrauma-related deaths in Moscow: Retrospective analysis of 969 autopsy studies.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. What trauma patients need: the European dilemma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shang-Lin HsiehDepartment of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Chien-Han HsiaoDepartment of Linguistics, Indiana University, Bloomington, IN, USA.
Wen-Chu ChiangDepartment of Emergency Medicine, Yunlin Branch, National Taiwan University Hospital, Douliu City, Taiwan.
Sang Do ShinDepartment of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Sabariah Faizah JamaluddinFaculty of Medicine, Universiti Teknologi MARA, Shah Alam, Malaysia.
Do Ngoc SonCenter for Emergency Medicine, Bach Mai Hospital, Hanoi, Vietnam.
Ki Jeong HongDepartment of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Sun Jen-TangDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Weide TsaiDepartment of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Ding-Kuo ChienDepartment of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Wen-Han ChangDepartment of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Tse-Hao ChenDepartment of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan. 99311121@gms.tcu.edu.tw.ORCID http://orcid.org/0000-0002-6370-7068
PATOS Clinical Research Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study examined the association between lapsed time and trauma patients, suggesting that a shorter time to definitive care leads to a better outcome.

methodsWe used the Pan-Asian Trauma Outcome Study registry to analyze a retrospective cohort of 963 trauma patients who received surgical intervention or transarterial embolization within 2 h of injury in Asian countries between January 2016 and December 2020. Exposure measurement was recorded every 30 min from injury to definitive care. The 30 day mortality rate and functional outcome were studied using the Modified Rankin Scale ratings of 0-3 vs 4-6 for favorable vs poor functional outcomes, respectively. Subgroup analyses of different injury severities and patterns were performed.

resultsThe mean time from injury to definitive care was 1.28 ± 0.69 h, with cases categorized into the following subgroups: < 30, 30-60, 60-90, and 90-120 min. For all patients, a longer interval was positively associated with the 30 day mortality rate (p = 0.053) and poor functional outcome (p < 0.05). Subgroup analyses showed the same association in the major trauma (n = 321, p < 0.05) and torso injury groups (n = 388, p < 0.01) with the 30 day mortality rate and in the major trauma (p < 0.01), traumatic brain injury (n = 741, p < 0.05), and torso injury (p < 0.05) groups with the poor functional outcome.

conclusionEven within 2 h, a shorter time to definitive care is positively associated with patient survival and functional outcome, especially in the subgroups of major trauma and torso injury.

Indexed as

Brain Injuries, TraumaticCohort StudiesHumansInjury Severity ScoreRegistriesRetrospective StudiesTrauma CentersGolden hourPan-Asia trauma outcomes studyPATOSTime to definitive careTrauma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.