Evidence map›Paper›PMID 34825249›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2022

Medium-term and peri-lockdown course of psychosocial burden during the ongoing COVID-19 pandemic: a longitudinal study on patients with pre-existing mental disorders.

Claudia Bartels, Philipp Hessmann, Ulrike Schmidt, Jonathan Vogelgsang, Mirjana Ruhleder, Alexander Kratzenberg, Marit Treptow, Thorgund Reh-Bergen, Mona Abdel-Hamid, Luisa Heß and 8 more

Open access · hybridAbstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Dissociative symptoms during the SARS-CoV-2 pandemic situation in mental health patients.Borderline personality disorder and emotion dysregulation · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 5 countries.

Claudia BartelsDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany. claudia.bartels@med.uni-goettingen.de.ORCID http://orcid.org/0000-0003-3023-9971
Philipp HessmannDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Ulrike SchmidtDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Jonathan VogelgsangDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Mirjana RuhlederDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Alexander KratzenbergDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Marit TreptowDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Thorgund Reh-BergenDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Mona Abdel-HamidDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Luisa HeßDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Miriam MeiserDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Jörg Signerski-KriegerDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Katrin RadenbachDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Sarah TrostDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Björn H SchottDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Jens WiltfangDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Claus Wolff-Menzler *Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
Michael Belz *Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, von-Siebold-Str. 5, 37075, Goettingen, Germany.
German Center for Neurodegenerative Diseases · DEFelix Platter-Hospital · CHHarvard University · USNephrologisches Zentrum Goettingen · DEUniversity Hospital Bonn · DEUniversity of Duisburg-Essen · DE

Funding

bundesministerium für bildung und forschung #01KX2021
6 · The paper itself

Abstract

While the COVID-19 pandemic continues, patients with pre-existing mental disorders are increasingly recognized as a risk group for adverse outcomes. However, data are conflicting and cover only short time spans so far. Here, we investigate the medium-term and peri-lockdown-related changes of mental health outcomes in such patients in a longitudinal study. A cohort of 159 patients comprising all major mental disorders (ICD-10 F0-F9) were interviewed twice with the Goettingen psychosocial Burden and Symptom Inventory (Goe-BSI) to evaluate psychosocial burden, psychiatric symptoms and resilience at the end of the first (April/May 2020) and the second lockdown in Germany (November/December 2020). For the primary outcome "psychosocial burden" ratings also comprised retrospective pre-pandemic (early 2020) and very early states during the pandemic (March 2020). For all diagnostic groups, psychosocial burden varied significantly over time (p < 0.001) with an increase from the pre-pandemic to the initial phase (p < 0.001), followed by a steady decrease across both lockdowns, normalizing in November/December 2020. Female gender, high adjustment disorder symptom load at baseline and psychiatric comorbidities were risk factors for higher levels and an unfavorable course of psychosocial burden. Most psychiatric symptoms changed minimally, while resilience decreased over time (p = 0.044 and p = 0.037). The longitudinal course of psychosocial burden indicates an initial stress response, followed by a return to pre-pandemic levels even under recurrent lockdown conditions, mimicking symptoms of an adjustment disorder. Strategies for proactive, specific and continuous treatment have to address resilience capacities before their depletion in the pandemic aftermath, especially for patients with additional risk factors.

Indexed as

COVID-19Mental DisordersCommunicable Disease ControlFemaleHumansLongitudinal StudiesMental HealthPandemicsRetrospective StudiesSARS-CoV-2Adjustment disorderCoronavirusMental healthPsychosocial stressSARS-CoV-2

Identifiers

PMID34825249
PMCPMC8614217
OpenAlexW3215829130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.