Evidence map›Paper›PMID 34825189›Full record

ArticleRSC medicinal chemistry2021

Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties.

Ivana Cacciatore, Hasan Turkez, Annalisa Di Rienzo, Michele Ciulla, Adil Mardinoglu, Antonio Di Stefano

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Ivana CacciatoreDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara via dei Vestini 31 66100 Chieti Scalo CH Italy ivana.cacciatore@unich.it.ORCID https://orcid.org/0000-0001-6253-0443
Hasan TurkezFaculty of Science, Basic Medical Sciences, Medical Biology Department, Ataturk University 25240 Yakutiye Erzurum Turkey.
Annalisa Di RienzoDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara via dei Vestini 31 66100 Chieti Scalo CH Italy ivana.cacciatore@unich.it.
Michele CiullaDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara via dei Vestini 31 66100 Chieti Scalo CH Italy ivana.cacciatore@unich.it.
Adil MardinogluScience for Life Laboratory, KTH, Royal Institute of Technology 24075 Stockholm Sweden.
Antonio Di StefanoDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara via dei Vestini 31 66100 Chieti Scalo CH Italy ivana.cacciatore@unich.it.
University of Chieti-Pescara · ITAtatürk University · TRKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel boron-based compounds (BBCs) were synthesized and evaluated as potential candidates for the development of novel drugs against Alzheimer's disease (AD). The neuroprotective profile of novel BBCs was evaluated using Aβ1-42-treated-SH-SY5Y cells while their antioxidant activity was evaluated by total antioxidant capacity (TAC) and total oxidative status (TOS) assays. Results showed that

Identifiers

PMID34825189
PMCPMC8597428
OpenAlexW3195949579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.