Evidence map›Paper›PMID 34825142›Full record

ArticleiScience2021

Neural responses in retrosplenial cortex associated with environmental alterations.

Lucas C Carstensen, Andrew S Alexander, G William Chapman, Aubrey J Lee, Michael E Hasselmo

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lucas C CarstensenCenter for Systems Neuroscience, Boston University, 610 Commonwealth Avenue, Boston, MA 02215, USA.
Andrew S AlexanderCenter for Systems Neuroscience, Boston University, 610 Commonwealth Avenue, Boston, MA 02215, USA.
G William ChapmanCenter for Systems Neuroscience, Boston University, 610 Commonwealth Avenue, Boston, MA 02215, USA.
Aubrey J LeeCenter for Systems Neuroscience, Boston University, 610 Commonwealth Avenue, Boston, MA 02215, USA.
Michael E HasselmoCenter for Systems Neuroscience, Boston University, 610 Commonwealth Avenue, Boston, MA 02215, USA.
Boston University · US

Funding

COMPARATIVE COGNITION AND HIPPOCAMPAL FUNCTIONR01MH052090 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI HASSELMO, MICHAEL E · 1994 to 2020
$6.4M
Egocentric and Allocentric Spatial Coding in CortexR01MH120073 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HASSELMO, MICHAEL E · 2019 to 2023
$2.5M
NIMH NIH HHS R01 MH052090NIMH NIH HHS R01 MH120073
6 · The paper itself

Abstract

The retrosplenial cortex (RSC) is an area interconnected with regions of the brain that display spatial correlates. Neurons in connected regions may encode an animal's position in the environment and location or proximity to objects or boundaries. RSC has also been shown to be important for spatial memory, such as tracking distance from and between landmarks, contextual information, and orientation within an environment. For these reasons, it is important to determine how neurons in RSC represent cues such as objects or boundaries and their relationship to the environment. In the current work, we performed electrophysiological recordings in RSC, whereas rats foraged in arenas that could contain an object or in which the environment was altered. We report RSC neurons display changes in mean firing rate responding to alterations of the environment. These alterations include the arena rotating, changing size or shape, or an object being introduced into the arena.

Indexed as

Animal physiologyBehavioral neuroscienceCellular neuroscienceNeuroscience

Identifiers

PMID34825142
PMCPMC8605176
OpenAlexW3209582902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.