Evidence map›Paper›PMID 34825031›Full record

ArticleData in brief2021

Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons.

Elizaveta A Dutysheva, Irina A Utepova, Maria A Trestsova, Alexander S Anisimov, Valery N Charushin, Oleg N Chupakhin, Boris A Margulis, Irina V Guzhova, Vladimir F Lazarev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elizaveta A DutyshevaRussian Academy of Sciences, Institute of Cytology, St. Petersburg 194064, Russia.
Irina A UtepovaUral Federal University, Ekaterinburg 620002, Russia.
Maria A TrestsovaUral Federal University, Ekaterinburg 620002, Russia.
Alexander S AnisimovRussian Academy of Sciences, Institute of Cytology, St. Petersburg 194064, Russia.
Valery N CharushinUral Federal University, Ekaterinburg 620002, Russia.
Oleg N ChupakhinUral Federal University, Ekaterinburg 620002, Russia.
Boris A MargulisRussian Academy of Sciences, Institute of Cytology, St. Petersburg 194064, Russia.
Irina V GuzhovaRussian Academy of Sciences, Institute of Cytology, St. Petersburg 194064, Russia.
Vladimir F LazarevRussian Academy of Sciences, Institute of Cytology, St. Petersburg 194064, Russia.
Institute of Cytology · RUUral Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

These data are related to our previous paper "Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease" (Dutysheva et al., 2021), in which we demonstrate neuroprotective abilities of pyrrolyl- and indolylazines in a cell model of Alzheimer's disease. Using a novel procedure of photocatalysis we have synthesized a group of new compounds. The current article presents nuclear magnetic resonance spectra including heteronuclear single quantum coherence spectra of chemicals synthesized by us. The effect of new compounds have on heat shock proteins genes expression in reprogrammed human neurons are presented. We also presented data that verify neuronal phenotype of reprogrammed cells.

Indexed as

Green chemistryHeat shock genesIndolylazinesNuclear magnetic resonancePhotocatalysisPyrrolylazines

Identifiers

PMID34825031
PMCPMC8605230
OpenAlexW3213444474

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.