Evidence map›Paper›PMID 34824806›Full record

ArticleEcology and evolution2021

Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of

Aigi Margus, Saija Piiroinen, Philipp Lehmann, Alessandro Grapputo, Leona Gilbert, Yolanda H Chen, Leena Lindström

Abstract read
In one paragraph

Article in Ecology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aigi MargusDepartment of Biological and Environmental Science University of Jyväskylä Jyväskylä Finland.ORCID https://orcid.org/0000-0002-2546-8238
Saija PiiroinenDepartment of Biological and Environmental Science University of Jyväskylä Jyväskylä Finland.
Philipp LehmannDepartment of Biological and Environmental Science University of Jyväskylä Jyväskylä Finland.ORCID https://orcid.org/0000-0001-8344-6830
Alessandro GrapputoDepartment of Biology University of Padua Padua Italy.ORCID https://orcid.org/0000-0001-9255-4294
Leona GilbertTe?ted Oy Jyväskylä Finland.ORCID https://orcid.org/0000-0002-7470-5770
Yolanda H ChenDepartment of Plant and Soil Science University of Vermont Burlington Vermont USA.ORCID https://orcid.org/0000-0001-9439-5899
Leena LindströmDepartment of Biological and Environmental Science University of Jyväskylä Jyväskylä Finland.ORCID https://orcid.org/0000-0002-6452-4538

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although insect herbivores are known to evolve resistance to insecticides through multiple genetic mechanisms, resistance in individual species has been assumed to follow the same mechanism. While both mutations in the target site insensitivity and increased amplification are known to contribute to insecticide resistance, little is known about the degree to which geographic populations of the same species differ at the target site in a response to insecticides. We tested structural (e.g., mutation profiles) and regulatory (e.g., the gene expression of

Indexed as

carbamategene expressioninsecticide resistanceorganophosphatetarget site mutation

Identifiers

PMID34824806
PMCPMC8601895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.