ArticleJournal of clinical and experimental dentistry2021
The inhibitory effect of a novel neem paste against cariogenic bacteria.
Article in Journal of clinical and experimental dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Integrated Virtual Screening for Anti-Caries Compounds from Neem: Dual-Target Inhibition of Biofilm Formation and Bacterial DNA Replication.Biomedicines · 2025Article
- Plant polyphenols, terpenes, and terpenoids in oral health.Open medicine (Warsaw, Poland) · 2025Review
- Unveiling the Neem (Plants (Basel, Switzerland) · 2024Article
- Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis.Antioxidants (Basel, Switzerland) · 2023Article
- Neem leaf powder (Azadirachta indica) mitigates oxidative stress and pathological alterations triggered by lead toxicity in Nile tilapia (Oreochromis niloticus).Scientific reports · 2023Article
- The Antimicrobial Potential of the Neem TreeFrontiers in pharmacology · 2022Review
- Dose-dependent effects of neem crude extract on human dental pulp cell and murine osteoblast viability and mineralization.Brazilian dental journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental caries is a major oral health problem, which associates with cariogenic bacteria. MATERIAL AND
methodsThe neem extract was derived from maceration of dry neem leaves in ethanol for 48 h. The ethanolic extract was subjected to chemical identification using GC-MS. Neem pastes were prepared from ethanolic extract mixed with polyethylene glycol paste with or without zinc oxide.
resultsGC-MS result displayed 35 compounds. Compounds found in the extract were n-Hexadecanoic acid (31.18%), Hentriacontane (18%), Phytol (16.79%). Disc diffusion showed that ethanolic extract and neem pastes inhibited growth of both bacteria. For MBC, neem paste with zinc oxide at concentration of neem 0.4 mg/ml was the most effective concentration on inhibiting
conclusionsThe ethanolic neem leaf extract and novel neem pastes had antimicrobial effect on both
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.